Evidence map›Paper›PMID 37069008›Full record

ArticleSurgery2023

Shifting paradigms for the treatment of ductal carcinoma in situ: Less is more.

Candice A M Sauder, Hira Abidi, Richard J Bold

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Candice A M SauderDivision of Surgical Oncology, Department of Surgery, University of California Davis Medical Center, Sacramento, CA; University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, Sacramento CA. Electronic address: camsauder@ucdavis.edu.
Hira AbidiDivision of Surgical Oncology, Department of Surgery, University of California Davis Medical Center, Sacramento, CA; University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, Sacramento CA.
Richard J BoldDivision of Surgical Oncology, Department of Surgery, University of California Davis Medical Center, Sacramento, CA; University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, Sacramento CA.

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

Ductal carcinoma in situ is a diverse disease in which only 50% of lesions progress to invasive carcinoma, but unfortunately, all patients receive similar treatment recommendations independent of the disease variability. De-escalation is the philosophy that treatment for this disease should be differentiated based on the likelihood of future progression and recurrence. Four surgical trials are looking at the possibility of removing surgical intervention, the current mainstay of treatment, from the algorithm. Molecular assays have been developed to help differentiate the risk of an ipsilateral breast tumor recurrence and potentially guide the postsurgical utility of radiation therapy. Primary endocrine therapy is also being explored as an alternative to standard local therapy. Ductal carcinoma in situ therapy is a very complicated algorithm that should be discussed and treated through shared decision-making.

Indexed as

Breast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingBreastCombined Modality TherapyFemaleHumansMastectomy, SegmentalNeoplasm Recurrence, Local

Identifiers

PMID37069008
PMCPMC12865923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.