Evidence map›Paper›PMID 37068914›Full record

ArticleRMD open2023

Patient appropriateness for total knee arthroplasty and predicted probability of a good outcome.

Gillian A Hawker, Eric Bohm, Michael J Dunbar, Peter Faris, C Allyson Jones, Tom Noseworthy, Bheeshma Ravi, Linda J Woodhouse, Deborah A Marshall, BEST-Knee Study Team

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07069179 narecruitingnot on this mapstarted 2025, after this paper: background citation

Choose to Move Replacement Ready: A Feasibility Trial of a Virtual Health-promoting Intervention for People Awaiting Total Hip or Knee Replacement Surgery

TypeinterventionalSponsorUniversity of British ColumbiaRan2025 to 2028Enrolled60ConditionsOsteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee ArthroplastyArmsChoose to Move Replacement Ready
NCT07696650 narecruitingnot on this mapstarted 2026, after this paper: background citation

Choose to Move Replacement Ready: Implementation and Effectiveness of a Virtual Health-Promoting Intervention for People Awaiting Total Hip or Knee Replacement Surgery

TypeinterventionalSponsorUniversity of British ColumbiaRan2026 to 2028Enrolled210ConditionsOsteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee AnthroplastyArmsChoose to Move Replacement Ready
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Gillian A HawkerDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada g.hawker@utoronto.ca.ORCID 0000-0001-6358-1197
Eric BohmDepartment of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Michael J DunbarDepartment of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
Peter FarisDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
C Allyson JonesDepartment of Physical Therapy, University of Alberta, Edmonton, Alberta, Canada.
Tom NoseworthyDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Bheeshma RaviDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Linda J WoodhouseDepartment of Physical Therapy, University of Alberta, Edmonton, Alberta, Canada.
Deborah A MarshallDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
BEST-Knee Study Team
University of Calgary · CAUniversity of Toronto · CADalhousie University · CATufts University · USUniversity of Alberta · CAUniversity of Manitoba · CA

Funding

CIHR MOP-312807
6 · The paper itself

Abstract

objectivesOne-fifth of total knee arthroplasty (TKA) recipients experience a suboptimal outcome. Incorporation of patients' preferences in TKA assessment may improve outcomes. We determined the discriminant ability of preoperative measures of TKA need, readiness/willingness and expectations for a good TKA outcome.

methodsIn patients with knee osteoarthritis (OA) undergoing primary TKA, we preoperatively assessed TKA need (Western Ontario-McMaster Universities OA Index (WOMAC) Pain Score and Knee injury and Osteoarthritis Outcome Score (KOOS) function, arthritis coping), health status, readiness (Patient Acceptable Symptom State, depressive symptoms), willingness (definitely yes-yes/no) and expectations (outcomes deemed 'very important'). A good outcome was defined as symptom improvement (met Outcome Measures in Rheumatology and Osteoarthritis Research Society International (OMERACT-OARSI) responder criteria) and satisfaction with results 1 year post TKA. Using logistic regression, we assessed independent outcome predictors, model discrimination (area under the receiver operating characteristic curve, AUC) and the predicted probability of a good outcome for different need, readiness/willingness and expectations scenarios.

resultsOf 1,053 TKA recipients (mean age 66.9 years (SD 8.8); 58.6% women), 78.1% achieved a good outcome. With TKA need alone (WOMAC pain subscale, KOOS physical function short-form), model discrimination was good (AUC 0.67, 95% CI 0.63 to 0.71). Inclusion of readiness/willingness, depressive symptoms and expectations regarding kneeling, stair climbing, well-being and performing recreational activities improved discrimination (p=0.01; optimism corrected AUC 0.70, 0.66-0.74). The predicted probability of a good outcome ranged from 44.4% (33.9-55.5) to 92.4% (88.4-95.1) depending on level of TKA need, readiness/willingness, depressive symptoms and surgical expectations.

conclusionsAlthough external validation is required, our findings suggest that incorporation of patients' TKA readiness, willingness and expectations in TKA decision-making may improve the proportion of recipients that experience a good outcome.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeAgedFemaleHumansMaleOutcome Assessment, Health CarePainTreatment OutcomeKnee OsteoarthritisOrthopedic ProceduresOsteoarthritis, KneeOutcomes research

Identifiers

PMID37068914
PMCPMC10111922
OpenAlexW4366084698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.