Evidence map›Paper›PMID 37068903›Full record

ArticleBMJ open2023

Comparing relationships between single types of adverse childhood experiences and health-related outcomes: a combined primary data study of eight cross-sectional surveys in England and Wales.

Mark A Bellis, Karen Hughes, Katie Cresswell, Kat Ford

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  13. Patterns of Adverse Childhood Experiences from a Longitudinal South African Community Sample: A Latent Class Analysis.International journal on child maltreatment : research, policy and practice · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mark A BellisFaculty of Health, Liverpool John Moores University, Liverpool, UK m.a.bellis@ljmu.ac.uk.ORCID 0000-0001-6980-1963
Karen HughesWHO Collaborating Centre for Investment in Health & Well-being, Public Health Wales, Wrexham, UK.
Katie CresswellPublic Health Collaborating Unit, School of Medical and Health Sciences, Bangor University, Bangor, UK.
Kat FordPublic Health Collaborating Unit, School of Medical and Health Sciences, Bangor University, Bangor, UK.ORCID 0000-0002-2984-5838
Bangor University · GBPublic Health Wales · GB

Funding

Medical Research Council MR/V049879/1
6 · The paper itself

Abstract

objectivesAdverse childhood experiences (ACEs) show strong cumulative associations with ill-health across the life course. Harms can arise even in those exposed to a single ACE type but few studies examine such exposure. For individuals experiencing a single ACE type, we examine which ACEs are most strongly related to different health harms.

designSecondary analysis of combined data from eight cross-sectional general population ACE surveys.

settingHouseholds in England and Wales.

participants20 556 residents aged 18-69 years. MEASURES: Ten self-reported outcomes were examined: smoking, cannabis use, binge drinking, obesity, sexually transmitted infection, teenage pregnancy, mental well-being, violence perpetration, violence victimisation and incarceration. Adjusted ORs and percentage changes in outcomes were calculated for each type of ACE exposure.

resultsSignificance and magnitude of associations between each ACE and outcome varied. Binge drinking was associated with childhood verbal abuse (VA), parental separation (PS) and household alcohol problem (AP), while obesity was linked to sexual abuse (SA) and household mental illness. SA also showed the biggest increase in cannabis use (25.5% vs 10.8%, no ACEs). Household AP was the ACE most strongly associated with violence and incarceration. PS was associated with teenage pregnancy (9.1% vs 3.7%, no ACEs) and 5 other outcomes. VA was associated with 7 of the 10 outcomes examined.

conclusionExposure to a single ACE increases risks of poorer outcomes across health-harming behaviours, sexual health, mental well-being and criminal domains. Toxic stress can arise from ACEs such as physical and SA but other more prevalent ACEs (eg, VA, PS) may also contribute substantively to poorer life course health.

Indexed as

Adverse Childhood ExperiencesBinge DrinkingAdolescentCross-Sectional StudiesEnglandFemaleHumansObesityPregnancyWalesChild protectionCommunity child healthMENTAL HEALTHPUBLIC HEALTHQuality of LifeSubstance misuse

Identifiers

PMID37068903
PMCPMC10111913
OpenAlexW4366084756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.