Evidence map›Paper›PMID 37068254›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Merged magnetic resonance and light sheet microscopy of the whole mouse brain.

G Allan Johnson, Yuqi Tian, David G Ashbrook, Gary P Cofer, James J Cook, James C Gee, Adam Hall, Kathryn Hornburg, Catherine C Kaczorowski, Yi Qi and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
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  8. Review
  9. MR-AIV revealsbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
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  12. From Circuits to Lifespan: Translating Mouse and Human Timelines with Neuroimaging-Based Tractography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Mid-Infrared Energy Deposition Spectroscopy.Physical review letters · 2025
    Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

G Allan JohnsonCenter for In Vivo Microscopy, Duke University, Durham, NC 27710.ORCID 0000-0002-7606-5447
Yuqi TianCenter for In Vivo Microscopy, Duke University, Durham, NC 27710.
David G AshbrookDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38162.ORCID 0000-0002-7397-8910
Gary P CoferCenter for In Vivo Microscopy, Duke University, Durham, NC 27710.
James J CookCenter for In Vivo Microscopy, Duke University, Durham, NC 27710.
James C GeeDepartment of Radiology, University of Pennsylvania, Philadelphia, PA 19104.
Adam HallLifeCanvas Technology, Cambridge, MA 02141.
Kathryn HornburgCenter for In Vivo Microscopy, Duke University, Durham, NC 27710.ORCID 0000-0003-3851-8297
Catherine C KaczorowskiDepartment of Neurology, University of Michigan, Ann Arbor, MI 48105
Yi QiCenter for In Vivo Microscopy, Duke University, Durham, NC 27710.ORCID 0000-0002-5365-5583
Fang-Cheng YehDepartment of Neurologic Surgery, University of Pittsburgh, Pittsburgh, PA 15260.
Nian WangDepartment of Radiology, Indiana University, Bloomington, IN 47401.ORCID 0000-0001-6547-8580
Leonard E WhiteDepartment of Neurology, Duke University, Durham, NC 27710.ORCID 0000-0002-5238-5120
Robert W WilliamsDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38162.

Funding

INTEGRATED CENTER FOR IN VIVO MICROSCOPYP41EB015897 · NIBIB · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2012 to 2017
$7.4M
Imaging Genetics of Brain Structure and Cognitive Aging in Murine Models of Alzheimer's DiseaseR01AG070913 · NIA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JOHNSON, GEORGE ALLAN, WILLIAMS, ROBERT W. · 2021 to 2025
$6.1M
Ultra-high Resolution Structural Connectome Atlases of the Animal Brain and their Associated ToolboxR01NS120954 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FANG-CHENG YEH · 2022 to 2026
$2.8M
Characterization of Whole Brain Demyelination and Axon Damage Using High-resolution Magnetic Resonance ImagingR01NS125020 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI Nian Wang · 2022 to 2026
$2.0M
Agilent Direct Drive 9.4T MRS/MRI ConsoleS10OD010683 · OD · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2012 to 2012
$597k
Construction of a high-resolution human tractography atlas and its related toolboxR56MH113634 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YEH, FANG-CHENG · 2018 to 2018
$452k
NIA NIH HHS R01 AG070913NIBIB NIH HHS P41 EB015897NIH HHS S10 OD010683NIMH NIH HHS R56 MH113634NINDS NIH HHS R01 NS120954NINDS NIH HHS R01 NS125020
6 · The paper itself

Abstract

We have developed workflows to align 3D magnetic resonance histology (MRH) of the mouse brain with light sheet microscopy (LSM) and 3D delineations of the same specimen. We start with MRH of the brain in the skull with gradient echo and diffusion tensor imaging (DTI) at 15 μm isotropic resolution which is ~

Indexed as

Diffusion Tensor ImagingMicroscopyAnimalsBrainDiffusion Magnetic Resonance ImagingMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiceconnectomelight sheet microscopymagnetic resonance histologymouse brain

Identifiers

PMID37068254
PMCPMC10151475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.