Evidence map›Paper›PMID 37068126›Full record

ReviewACS applied bio materials2023

Harnessing Biomaterials to Study and Direct Antigen-Specific Immunotherapy.

Camilla Edwards, Sean T Carey, Christopher M Jewell

Open access · greenAbstract readReview
In one paragraph

Review in ACS applied bio materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Exploiting Unique Features of Microneedles to Modulate Immunity.Advanced materials (Deerfield Beach, Fla.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Camilla EdwardsUniversity of Maryland Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States.
Sean T CareyUniversity of Maryland Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States.ORCID 0000-0003-1851-0300
Christopher M JewellUniversity of Maryland Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States.ORCID 0000-0002-6668-6928
University of Maryland, College Park · USUniversity of Maryland, Baltimore · US

Funding

Training Grant in Cancer BiologyT32CA154274 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Toni M Antalis, CURT I CIVIN · 2011 to 2026
$6.8M
Defining the induction and maintenance of myelin-specific tolerance in T cells and B cells using local lymph node depotsR01AI169686 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI Christopher M Jewell · 2022 to 2026
$2.8M
Training in Host-pathogens interactionsT32AI089621 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI LEE, VINCENT T, MCIVER, KEVIN S. · 2010 to 2025
$2.1M
Improving multiple sclerosis patient quality of life using microneedle patches to simplify delivery of MS drugsR01AI144667 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI JEWELL, CHRISTOPHER M · 2019 to 2022
$1.6M
Programming immune function through modular assembly of polyionic immune signalsR01EB027143 · NIBIB · UNIV OF MARYLAND, COLLEGE PARK · PI JEWELL, CHRISTOPHER M · 2019 to 2022
$1.6M
Tunable Assembly of Regulatory Immune Signals to Promote Myelin-specific ToleranceI01BX003690 · VA · BALTIMORE VA MEDICAL CENTER · PI Christopher M Jewell · 2017 to 2026
–
BLRD VA I01 BX003690NCI NIH HHS T32 CA154274NIAID NIH HHS R01 AI144667NIAID NIH HHS R01 AI169686NIAID NIH HHS T32 AI089621NIBIB NIH HHS R01 EB027143
6 · The paper itself

Abstract

Immunotherapies are an evolving treatment paradigm for addressing cancer, autoimmunity, and infection. While exciting, most of the existing therapies are limited by their specificity─unable to differentiate between healthy and diseased cells at an antigen-specific level. Biomaterials are a powerful tool that enable the development of next-generation immunotherapies due to their tunable synthesis properties. Our lab harnesses biomaterials as tools to study antigen-specific immunity and as technologies to enable new therapeutic vaccines and immunotherapies to combat cancer, autoimmunity, and infections. Our efforts have spanned the study of intrinsic immune profiles of biomaterials, development of novel nanotechnologies assembled entirely from immune cues, manipulation of innate immune signaling, and advanced technologies to direct and control specialized immune niches such as skin and lymph nodes.

Indexed as

Biocompatible MaterialsNeoplasmsAntigensHumansImmunotherapySignal TransductionAntigensBiocompatible Materialsautoimmunitybiomaterialsimmune engineeringimmunologynanotechnologyvaccine

Identifiers

PMID37068126
PMCPMC10330265
OpenAlexW4366141658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.