ArticleInternational ophthalmology2023
A comparison between bilateral and unilateral thyroid eye disease.
Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease.Acta ophthalmologica · 2026Article
- Article
- Novel immunoinflammatory blood markers in Graves' orbitopathy: insights into activity and severity.BMJ open ophthalmology · 2024Article
- Catastrophic Sequelae of Corneal Melt from Severe Active Thyroid Eye Disease in a Patient with Substance Use Disorder: A Case Report.Case reports in ophthalmologyArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare characteristics of unilateral vs. bilateral thyroid eye disease (TED).
methodsThis retrospective analytical cross-sectional study was conducted on patients with TED who were evaluated at an academic referral center over a 6-year period. We compared demographics, activity (clinical activity score) and severity (EUGOGO classification) of TED, thyroid disease duration, TED duration, the time interval between thyroid and eye involvement, thyroid function status, and clinical signs between bilateral and unilateral TED.
resultsThree hundred eighty-three patients including 213 females (55.6%), who had a mean age of 40.23 ± 13.72 years, were enrolled. Active TED was seen in 8.8% of bilateral and none of unilateral cases (P = 0.04). Bilateral TED patients had more severe disease (P = 0.001). The distribution of hyperthyroidism, hypothyroidism, and euthyroidism was significantly different between unilateral and bilateral groups (P = 0.001). Abnormal ocular motility was present in 26.3% versus 2.3% of bilateral and unilateral ones, respectively (P = 0.001). Proptosis was more prevalent in bilateral than unilateral cases (P = 0.001). We did not observe any statistically significant difference between the two groups in others variables.
conclusionBilateral TED patients present with more severity, activity, movement abnormality, proptosis, and hyperthyroidism.
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