Evidence map›Paper›PMID 37067425›Full record

ArticleMicrobiology resource announcements2023

Draft Genome Sequences and Genome Characterization of Three Toxigenic and Two Nontoxigenic Clostridioides difficile Clinical Isolates from Florida, USA.

Ishani Wickramage, Joshua Heuler, Zhong Peng, Sally Alrabaa, Xingmin Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology resource announcements, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ishani WickramageDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-0397-3428
Joshua HeulerDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Zhong PengDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Sally AlrabaaDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Xingmin SunDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-8900-9161

Funding

Multivalent vaccines against Clostridium difficile infectionR01AI132711 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI Xingmin Sun, Shifeng Wang · 2017 to 2026
$3.3M
Novel polymer biomaterials combating C. difficile infectionR01AI149852 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CAI, JIANFENG, SUN, XINGMIN · 2019 to 2023
$1.9M
Effect of bile salt hydrolase inhibitors on Clostridium difficile infectionR21AI159745 · NIAID · UNIVERSITY OF TENNESSEE KNOXVILLE · PI LIN, JUN, SUN, XINGMIN · 2021 to 2022
$416k
NIAID NIH HHS R01 AI132711NIAID NIH HHS R01 AI149852NIAID NIH HHS R21 AI159745NIH HHS R01-AI132711
6 · The paper itself

Abstract

Draft genome sequences of five Clostridioides difficile clinical isolates were obtained in Florida, USA. Three isolates, designated TGH29 (sequence type 1 [ST1]/clade 2), TGH79 (ST11/clade 5), and TGH91 (ST35/clade 1), contained toxin-encoding genes. The two nontoxigenic strains were classified as TGH114 (ST109/clade 4) and TGH132 (ST15/clade 1). Antimicrobial resistance determinants and plasmids were detected and putative prophages predicted in some isolates.

Identifiers

PMID37067425
PMCPMC10190669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.