SynthesisDiabetes technology & therapeutics2023
A Meta-Analysis of Randomized Trial Outcomes for the t:slim X2 Insulin Pump with Control-IQ Technology in Youth and Adults from Age 2 to 72.
Registry-linked trialOpen access · greenAbstract readMeta-Analysis
In one paragraph
Synthesis in Diabetes technology & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06834334 (Clinical Effectiveness of Advanced Hybrid Closed-loop Systems), which is not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
19.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Effectiveness of Advanced Hybrid Closed-loop Systems (AHCL) for Achieving Time in Tight Range (TiTR) of Interstitial Glucose Among Adult Type 1 Diabetes (T1D) Patients
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Equity of Continuous Glucose Monitoring in Children and Young People With Type 1 Diabetes: A Systematic Review.Pediatric diabetes · 2025Pooled it
- Efficacy of the hybrid closedloop insulin delivery system in children and adolescents with type 1 diabetes: a meta-analysis with trial sequential analysis.Archives of endocrinology and metabolism · 2024Pooled it
- International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024: Diabetes Technologies - Insulin Delivery.Hormone research in paediatrics · 2024Guideline
- Randomized, Crossover Trial of Control-IQ Technology with a Lower Treatment Range and a Modified Meal Bolus Module in Adults, Adolescents, Children, and Preschoolers with Varying Levels of Baseline Glycemic Control.Diabetes technology & therapeutics · 2025Trial
- Control-IQ Technology Use in Individuals With High Insulin Requirements: Results From the Multicenter Higher-IQ Trial.Journal of diabetes science and technology · 2024Trial
- Hybrid Closed Loop Systems Improve Glycemic Control and Quality of Life in Historically Minoritized Youth with Diabetes.Diabetes technology & therapeutics · 2024Trial
- Automated Insulin Delivery Use Among Preschool-Age Children With Type 1 Diabetes: A T1D Exchange Multicenter Analysis.Journal of diabetes science and technology · 2026Article
- Rethinking control-IQ+ technology: Simple strategies for easy optimization.Diabetes, obesity & metabolism · 2026Review
- Long-term efficacy and safety of Control-IQ technology in younger children with type 1 diabetes in Italy (2020-2023): a longitudinal multicentre real-world study.EClinicalMedicine · 2026Article
- 7. Diabetes Technology: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Real-World Experience With Control-IQ Technology in Saudi Children With Insulin-Dependent Diabetes: A Single-Center Observational Study.Pediatric diabetes · 2026Observational
- Prospective multicenter evaluation of glycemic and patient-reported outcomes following transition to a next-generation continuous glucose monitoring system in users of advanced hybrid closed-loop technology.Therapeutic advances in endocrinology and metabolism · 2026Article
- An overview of the t:slim X2 and Mobi insulin pumps with Control-IQ technology: patient safety and device efficacy.Expert review of medical devices · 2025Review
- Retrospective analysis of impact of automated insulin delivery technology on acute care utilisation from 2019 to 2021.Diabetic medicine : a journal of the British Diabetic Association · 2025Observational
- Evaluation of Glycemia Risk Index and Continuous Glucose Monitoring Outcomes Following the Transition to an Advanced Hybrid Closed-Loop System in Type 1 Diabetes.Advances in therapy · 2025Article
- Case series of a hybrid closed loop therapy system used in pregnancy.Acta diabetologica · 2025Article
- A Review of Real-World Evidence About the Use of Automated Insulin Delivery Systems in People With Type 1 Diabetes.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025Review
- Daytime and nighttime glycemic control with control-IQ technology vs. standard therapy in type 1 diabetes: a systematic review and meta-analysis with trial sequential analysis and GRADE assessment.Diabetology & metabolic syndrome · 2025Review
- Trends and Disparities in Technology Use and Glycemic Control in Type 1 Diabetes.JAMA network open · 2025Article
- The effects of self-compassion in adolescents and young adults with type 1 diabetes: a pilot randomized controlled trial.Annals of pediatric endocrinology & metabolism · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Roy W BeckJAEB Center for Health Research, Tampa, Florida, USA.ORCID 0000-0002-5194-8446
Lauren G KanapkaJAEB Center for Health Research, Tampa, Florida, USA.ORCID 0000-0003-4440-5168
Marc D BretonUniversity of Virginia Center for Diabetes Technology, Charlottesville, Virginia, USA.ORCID 0000-0001-7645-2693
Sue A BrownUniversity of Virginia Center for Diabetes Technology, Charlottesville, Virginia, USA.
R Paul WadwaBarbara Davis Center for Diabetes, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-4139-2122
Bruce A BuckinghamDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.
Craig KollmanJAEB Center for Health Research, Tampa, Florida, USA.
Boris KovatchevUniversity of Virginia Center for Diabetes Technology, Charlottesville, Virginia, USA.
Jaeb Center for Health Research · USUniversity of Virginia · USStanford Medicine · USUniversity of Colorado Anschutz Medical Campus · US
Funding
Translation of the UVA Advanced Automated Insulin Delivery Systems to Clinical Care in Young Children: Glycemic Control, Regulatory Acceptance and Optimization of Day to Day UseU01DK127551 · NIDDK · UNIVERSITY OF VIRGINIA · PI BRETON, MARC D, BUCKINGHAM, BRUCE A · 2020 to 2022
$4.4MAdvanced Artificial Pancreas Systems to Enable Fully Automated Glycemic Control in Type 1 Diabetes MellitusR01DK129553 · NIDDK · UNIVERSITY OF VIRGINIA · PI BRETON, MARC D, BROWN, SUE A · 2021 to 2025
$3.1MNIDDK NIH HHS R01 DK129553
Abstract
PubMed holds no abstract for this paper.
Indexed as
Diabetes Mellitus, Type 1HypoglycemiaAdolescentAdultAgedBlood GlucoseBlood Glucose Self-MonitoringChildChild, PreschoolGlycated HemoglobinHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsInsulin, Regular, HumanMiddle AgedBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinInsulin, Regular, HumanArtificial pancreasAutomated insulin deliveryType 1 diabetes
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT06834334ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.