Trial reportEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2023
Feasibility of redo-TAVI in self-expanding Evolut valves: a CT analysis from the Evolut Low Risk Trial substudy.
Trial report in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02701283 (Transcatheter Aortic Valve Replacement With the Medtronic Transcatheter Aortic Valve Replacement System In Patients at Low Risk for Surgical Aortic Valve Replacement), which is not on this map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transcatheter Aortic Valve Replacement With the Medtronic Transcatheter Aortic Valve Replacement System In Patients at Low Risk for Surgical Aortic Valve Replacement
Who cites it
25 citing papers in PubMed.
- Structural Valve Failure During Transcatheter Aortic Valve Replacement: Infolding, Deformation, Embolization, and Valve-In-Valve Rescue.JACC. Case reports · 2026Article
- Geometric coronary constraints and anatomical feasibility of redo TAVR in Asian patients with Evolut valves: A CT-based simulation study.Cardiovascular intervention and therapeutics · 2026Article
- Hypoattenuated Leaflet Thickening After TAVR: Incidence, Predictors, and the Role of Platelet Reactivity: A Prospective Multicenter Observational Study.Journal of clinical medicine · 2026Article
- Aortic Valve Leaflet Modification: A Working Group Position Statement on Best Practices and Step-by-Step Guide.JACC. Cardiovascular interventions · 2026Review
- Transcatheter aortic valve implantation for symptomatic severe aortic stenosis and its expanding clinical indications.The Korean journal of internal medicine · 2026Review
- TAVI-in-TAVI in a patient with morquio syndrome: a case report.European heart journal. Case reports · 2026Article
- The Age of Opportunity in Aortic Valve Interventions: Beyond Traditional Boundaries for Transcatheter Aortic Valve Replacement in Younger Patients.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Computed Tomography-Based Evaluation of Redo-Transcatheter Aortic Valve Replacement Feasibility for Self-Expanding Valves.Structural heart : the journal of the Heart Team · 2025Article
- Surgical vs. Medical Management of Infective Endocarditis Following TAVR: A Systematic Review and Meta-Analysis.Journal of cardiovascular development and disease · 2025Review
- Chimney stenting for preventing coronary obstruction in redo-TAVI with balloon-expandable valves within self-expanding valves.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Article
- Redo-Transcatheter Aortic Valve Replacement Procedural Optimization and Patient Selection: From Bench to Clinical Practice.Journal of clinical medicine · 2025Review
- Repeated Transcatheter Valve Interventions After Surgical Mitral Valve Replacement: A 20-Year Journey Avoiding Surgical Redo.CJC open · 2025Article
- How to avoid transcatheter aortic valve replacement explant as the second valve procedure: image assessment for the index transcatheter aortic valve replacement.Annals of cardiothoracic surgery · 2025Review
- Lifetime management considerations to optimise transcatheter aortic valve implantation: a practical guide.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Review
- Redo-TAVI with the SAPIEN 3 valve in degenerated calcified CoreValve/Evolut explants.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Feasibility of redo-TAVI in the self-expanding ACURATE neo2 valve: a computed tomography study.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Redo-TAVI feasibility and coronary accessibility following index TAVI with the Evolut valve in patients with bicuspid aortic valve stenosis.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Navitor™ in Evolut™: a case report illustrating a novel approach to redo-transcatheter aortic valve implantation.European heart journal. Case reports · 2024Article
- Impact of aortic root surgery during transcatheter aortic valve explant.JTCVS structural and endovascular · 2024Article
- Splitter - a novel device for leaflet modification in transcatheter aortic valve-in-valve implantation procedures.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundTranscatheter aortic valve implantation in an existing transcatheter valve (redo-TAVI) pins the index valve leaflets in the open position (neoskirt), which can cause coronary flow compromise and limit access. Whether anatomy may preclude redo-TAVI in self-expanding Evolut valves is unknown.
aimsWe aimed to evaluate the anatomical feasibility of redo-TAVI by simulating implantation of a balloon-expandable SAPIEN 3 (S3) within an Evolut or an Evolut within an Evolut.
methodsA total of 204 post-TAVI computed tomography (CT) scans from the Evolut Low Risk CT substudy were analysed. Five redo-TAVI positions were evaluated: S3-in-Evolut inflow-to-inflow, S3 outflow at Evolut nodes 4, 5, and 6, and Evolut-in-Evolut inflow-to-inflow. Univariable modelling identified pre-TAVI clinical characteristics, CT anatomical parameters, and procedural variables associated with coronary flow compromise using the neoskirt height and post-TAVI aortic root dimensions.
resultsThe risk of coronary flow compromise was lowest when the S3 outflow was at Evolut node 4 (20%) and highest when at Evolut node 6 (75%). The highest likelihood of preserving coronary accessibility occurred with the S3 outflow at Evolut node 4. Female sex and higher body mass index were associated with a higher risk of coronary flow compromise, as were a smaller annulus diameter, lower sinus of Valsalva height and width, shorter coronary height, smaller sinotubular junction diameter, and shallower Evolut implant depth.
conclusionsThe feasibility of redo-TAVI after Evolut failure is multifactorial and relates to the native annular anatomy, as well as the implantation depth of the index and second bioprostheses. Placement of an S3 at a lower Evolut position may reduce the risk of coronary flow compromise while preserving coronary access. CLINICALTRIALS: gov: NCT02701283.
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