Evidence map›Paper›PMID 37067150›Full record

ArticleeLife2023

BUB-1 and CENP-C recruit PLK-1 to control chromosome alignment and segregation during meiosis I in

Samuel J P Taylor, Laura Bel Borja, Flavie Soubigou, Jack Houston, Dhanya K Cheerambathur, Federico Pelisch

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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  13. Polo-like kinase 1 prevents excess microtubule polymerization inbioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Samuel J P Taylor *Centre for Gene Regulation and Expression, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-0654-619X
Laura Bel Borja *Centre for Gene Regulation and Expression, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-8381-934X
Flavie SoubigouCentre for Gene Regulation and Expression, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Jack HoustonLudwig Institute for Cancer Research, San Diego Branch, La Jolla, United States.
Dhanya K CheerambathurWellcome Centre for Cell Biology & Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Federico PelischCentre for Gene Regulation and Expression, Sir James Black Centre, School of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0003-4575-1492
Institute of Cancer Research · GBUniversity of Dundee · GBLudwig Cancer Research · BEWellcome Centre for Cell Biology · GB

Funding

Kinetochore Specification and FunctionR01GM074215 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DESAI, ARSHAD · 2005 to 2025
$8.2M
Medical Research Council MR/R008574/1Wellcome Trust 208833/Z/17/Z
6 · The paper itself

Abstract

Phosphorylation is a key post-translational modification that is utilised in many biological processes for the rapid and reversible regulation of protein localisation and activity. Polo-like kinase 1 (PLK-1) is essential for both mitotic and meiotic cell divisions, with key functions being conserved in eukaryotes. The roles and regulation of PLK-1 during mitosis have been well characterised. However, the discrete roles and regulation of PLK-1 during meiosis have remained obscure. Here, we used

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsChromosomal Proteins, Non-HistoneChromosome SegregationKinetochoresMeiosisOocytesPolo-Like Kinase 1Protein Serine-Threonine KinasesSpindle Apparatusbub-1 protein, C elegansCaenorhabditis elegans Proteinscentromere protein CChromosomal Proteins, Non-Histoneplk-1 protein, C elegansPolo-Like Kinase 1Protein Serine-Threonine KinasesC. eleganscell biologycentromerekinetochoremeiosisoocytePLK1

Identifiers

PMID37067150
PMCPMC10156168
OpenAlexW4366083972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.