ArticleTherapeutic advances in respiratory disease
Oxygen insufflation through the bronchoscope channel for sedation-induced hypoxia: safe and effective.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- A novel nasal cannula versus conventional face mask for preventing hypoxemia during flexible bronchoscopy in children: a randomized controlled trial.European journal of pediatrics · 2026Trial
- Evaluation of high flow nasal cannulae during endobronchial ultrasound bronchoscopy (EBUS) in high anaesthetic risk patients: a monocentric prospective study.BMC anesthesiology · 2025Observational
- Apnoeic Oxygenation Using High-Flow Oxygen: Effects on Partial Pressure of Carbon Dioxide in Rigid Bronchoscopy.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate both efficacy and safety parameters for insufflation through the bronchoscope as a method of recovery from sedation-induced hypoxia. To explore parameters applicable to use in human beings using an animal model. MATERIALS AND
methodsTwo adult pigs were sedated enough to depress respiratory drive. The effects of insufflation at 15 l/min (the upper limits of flow that might be used clinically) were then evaluated. Pressure and volume responses to bronchoscopy during intubation and without an endotracheal tube in place were recorded. Several assays were performed for each scenario, with each animal acting as its own control. Recovery from hypoxemia using insufflation was compared with recovery using mechanical ventilation.
resultsInsufflation was effective, with rapid increases in fraction of inspired oxygen (FIO
conclusionInsufflation through the bronchoscope for episodes of sedation-induced hypoxia should be safe and effective as long as not delivered within a closed system.
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Registered trials
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