ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2023
Study on the detection of anthrax by ICP-MS based on gold nanoparticle labeling.
Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
backgroundIn recent years, inductively coupled plasma mass spectrometry (ICP-MS) has been widely used in the field of molecular biology because of its unique advantages. Anthrax is a widespread and long-standing infectious disease, which affects and restricts people's work and life seriously.
objectiveThe study goal is to develop a new method for the detection of anthrax.
methodsA rapid, sensitive and accurate method for the detection of anthrax characteristic DNA was proposed by combing gold nanoparticles (AuNPs) and inductively coupled plasma mass spectrometry.
resultsThe linear range of this method is 100-2500 pmol/L and the limit of detection of 16.61 pmol/L.
conclusionThe proposed method has numerous advantages, including simplicity of operation, high sensitivity, and specificity, which provides a new idea for the detection of anthrax. Importantly, this methodology has good potential for the detection of other biological substances such as bacteria and viruses by changing the modification sequence on the nanoparticle probe.
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