Evidence map›Paper›PMID 37066400›Full record

ArticlebioRxiv : the preprint server for biology2023

Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system.

Victoria Røyseth, Brianna M Hurysz, Anna Kaczorowska, Sebastian Dorawa, Anita-Elin Fedøy, Hasan Arsin, Mateus Serafim, Olesia Werbowy, Tadeusz Kaczorowski, Runar Stokke and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Victoria RøysethDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Brianna M HuryszSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, USA.
Anna KaczorowskaCollection of Plasmids and Microorganisms | KPD, Faculty of Biology, University of Gdansk, Gdansk, Poland.
Sebastian DorawaLaboratory of Extremophiles Biology, Department of Microbiology, Faculty of Biology, University of Gdansk, Gdansk, Poland.
Anita-Elin FedøyDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Hasan ArsinDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Mateus SerafimSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, USA.
Olesia WerbowyLaboratory of Extremophiles Biology, Department of Microbiology, Faculty of Biology, University of Gdansk, Gdansk, Poland.
Tadeusz KaczorowskiLaboratory of Extremophiles Biology, Department of Microbiology, Faculty of Biology, University of Gdansk, Gdansk, Poland.
Runar StokkeDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
Anthony J O'DonoghueSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, USA.
Ida Helene SteenDepartment of Biological Sciences, Center for Deep Sea Research, University of Bergen, Bergen, Norway.
University of Bergen · NOUniversity of Gdańsk · PLUniversity of California San Diego · USUniversidade Federal de Minas Gerais · BR

Funding

GRADUATE TRAINING IN CELLULAR &MOLECULAR PHARMACOLOGYT32GM007752 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, JOAN HELLER, HANDEL, TRACY M · 1985 to 2023
$13.5M
NIGMS NIH HHS T32 GM007752
6 · The paper itself

Abstract

Deep-sea hydrothermal vent systems with prevailing extreme thermal conditions for life offer unique habitats to source heat tolearant enzymes with potential new enzymatic properties. Here, we present the novel C11 protease

Identifiers

PMID37066400
PMCPMC10104074
OpenAlexW4362636462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.