Evidence map›Paper›PMID 37066305›Full record

ArticlebioRxiv : the preprint server for biology2023

The Allen Ancient DNA Resource (AADR): A curated compendium of ancient human genomes.

Swapan Mallick, Adam Micco, Matthew Mah, Harald Ringbauer, Iosif Lazaridis, Iñigo Olalde, Nick Patterson, David Reich

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Swapan MallickDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Adam MiccoDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Matthew MahDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Harald RingbauerDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
Iosif LazaridisDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Iñigo OlaldeDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Nick PattersonBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.

Funding

Solving ascertainment bias in ancient DNA using Ultima Genomics sequencingR01HG012287 · NHGRI · HARVARD MEDICAL SCHOOL · PI REICH, DAVID E · 2021 to 2025
$2.7M
NHGRI NIH HHS R01 HG012287
6 · The paper itself

Abstract

More than two hundred papers have reported genome-wide data from ancient humans. While the raw data for the vast majority are fully publicly available testifying to the commitment of the paleogenomics community to open data, formats for both raw data and meta-data differ. There is thus a need for uniform curation and a centralized, version-controlled compendium that researchers can download, analyze, and reference. Since 2019, we have been maintaining the Allen Ancient DNA Resource (AADR), which aims to provide an up-to-date, curated version of the world's published ancient human DNA data, represented at more than a million single nucleotide polymorphisms (SNPs) at which almost all ancient individuals have been assayed. The AADR has gone through six public releases since it first was made available and crossed the threshold of >10,000 ancient individuals with genome-wide data at the end of 2022. This note is intended as a citable description of the AADR.

Identifiers

PMID37066305
PMCPMC10104067

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.