Evidence map›Paper›PMID 37066223›Full record

ArticlebioRxiv : the preprint server for biology2023

Interferon ε restricts Zika virus infection in the female reproductive tract.

Chuan Xu, Annie Wang, Laith Ebraham, Liam Sullivan, Carley Tasker, Vanessa Pizutelli, Jennifer Couret, Cyril Hernandez, Pratik Q Deb, Luke Fritzky and 11 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Chuan XuPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Annie WangPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Laith EbrahamPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Liam SullivanPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Carley TaskerPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Vanessa PizutelliPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Jennifer CouretDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Cyril HernandezPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Pratik Q DebDepartment of Pathology and Laboratory Medicine, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Luke FritzkyDepartment of Pathology and Laboratory Medicine, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Selvakumar SubbianPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Nan GaoDepartment of Cell Biology, Rutgers, School of Art and Science-Newark, Newark, NJ 07103, USA.
Yungtai LoDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY10461.
Mirella SalvatoreDepartment of Medicine, Weill Cornell Medical College, New York, NY, 10065.
Amariliz RiveraDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Alexander LemenzeDepartment of Pathology and Laboratory Medicine, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Patricia Fitzgerald-BocarslyDepartment of Pathology and Laboratory Medicine, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Sanjay TyagiPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Wuyuan LuKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Science, and Shanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai 200032, China.
Aimee BeaulieuDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Theresa L ChangPublic Health Research Institute, Rutgers, New Jersey Medical School, Newark, NJ 07103, USA.
Rutgers, The State University of New Jersey · USAlbert Einstein College of Medicine · USCornell University · USFudan University · CN

Funding

Background free amplified single-molecule FISH for in situ and flow cytometric applicationsR01CA227291 · NCI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI TYAGI, SANJAY · 2018 to 2022
$2.8M
NCI NIH HHS R01 CA227291
6 · The paper itself

Abstract

Interferon ε (IFNε) is a unique type I IFN that has been implicated in host defense against sexually transmitted infections (STIs). Zika virus (ZIKV), an emerging pathogen, can infect the female reproductive tract (FRT) and cause devastating diseases, particularly in pregnant women. How IFNε contributes to protection against ZIKV infection

Identifiers

PMID37066223
PMCPMC10104157
OpenAlexW4362721453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.