Evidence map›Paper›PMID 37066199›Full record

ArticlebioRxiv : the preprint server for biology2023

A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases.

Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero-Arguero, Chengjin Ye, Hao Zhang, Hong Cai, Yufeng Wang, Zhao Lai and 7 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Susanta PahariHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Eusondia ArnettHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Jan SimperHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Abul AzadHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Israel Guerrero-ArgueroHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Chengjin YeHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Hao ZhangDepartment of Molecular Microbiology and Immunology, South Texas Center for Emerging Infectious diseases, University of Texas at San Antonio, San Antonio, TX, USA.
Hong CaiDepartment of Molecular Microbiology and Immunology, South Texas Center for Emerging Infectious diseases, University of Texas at San Antonio, San Antonio, TX, USA.
Yufeng WangDepartment of Molecular Microbiology and Immunology, South Texas Center for Emerging Infectious diseases, University of Texas at San Antonio, San Antonio, TX, USA.
Zhao LaiDepartment of Molecular Medicine, UT Health San Antonio, San Antonio, TX, USA.
Natalie JarvisHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Miranda LumbrerasHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Diego Jose Maselli-CaceresDivision of Pulmonary and Critical Care Medicine, UT Health Science Center, San Antonio, TX 78207.
Jay PetersDivision of Pulmonary and Critical Care Medicine, UT Health Science Center, San Antonio, TX 78207.
Jordi B TorrellesHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Luis Martinez-SobridoHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Larry S SchlesingerHost Pathogen Interactions and Population Health programs, Texas Biomedical Research Institute, San Antonio, TX, USA.
Texas Biomedical Research Institute · USTexas Center for Infectious Disease · USThe University of Texas Health Science Center at San Antonio · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Interdisciplinary NexGen TB research Advancement Center (IN-TRAC)P30AI168439 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Shannan Hall-Ursone · 2022 to 2026
$6.9M
Macrophage nuclear receptors, metabolism and immune effectors during health and M. tuberculosis infection- Diversity SupplementR01AI136831 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Eusondia A. Arnett, Larry S. Schlesinger · 2019 to 2026
$4.6M
Mechanism-based Targeting of the RNA Processing Machinery of SARS-CoV-2R01AI161363 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GUPTA, YOGESH K · 2021 to 2025
$3.2M
Dynamics of the protective vaccine-induced human influenza neuraminidase B cell responseR01AI145332 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KOBIE, JAMES J, MARTINEZ-SOBRIDO, LUIS · 2019 to 2022
$3.0M
The origin and future protective activity of SARS-CoV-2 RBD specific neutralizing antibodiesR01AI161175 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KOBIE, JAMES J, MARTINEZ-SOBRIDO, LUIS · 2021 to 2024
$2.5M
High Throughput DNA Sequencer: Illumina HiSeq 3000 SequencerS10OD021805 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2016 to 2016
$600k
BD FACSymphonyS10OD028653 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI TURNER, JOANNE · 2020 to 2020
$463k
NCI NIH HHS P30 CA054174NIAID NIH HHS P30 AI168439NIAID NIH HHS R01 AI136831NIAID NIH HHS R01 AI145332NIAID NIH HHS R01 AI161175NIAID NIH HHS R01 AI161363NIH HHS S10 OD021805NIH HHS S10 OD028653
6 · The paper itself

Abstract

Alveolar macrophages (AMs) are unique lung resident cells that contact airborne pathogens and environmental particulates. The contribution of human AMs (HAM) to pulmonary diseases remains poorly understood due to difficulty in accessing them from human donors and their rapid phenotypic change during IMPORTANCE: Millions die annually from respiratory disorders. Lower respiratory track gas-exchanging alveoli maintain a precarious balance between fighting invaders and minimizing tissue damage. Key players herein are resident AMs. However, there are no easily accessible

Identifiers

PMID37066199
PMCPMC10104118
OpenAlexW4362716509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.