Evidence map›Paper›PMID 37066115›Full record

ArticleJID innovations : skin science from molecules to population health2023

Electrical Impedance Dermography Differentiates Squamous Cell Carcinoma In Situ from Inflamed Seborrheic Keratoses.

Elaine Wen-Ying Wong, Sarbesh Pandeya, Henry Crandall, Tristan Smart, Madisen Dixon, Kenneth M Boucher, Scott R Florell, Douglas Grossman, Benjamin Sanchez

Registry-linked trialAbstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07570056 (A Pilot Study for the Use of Electrical Bioimpedance in Acute Myeloid Leukemia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07570056 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Pilot Study for the Use of Electrical Bioimpedance in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients (Bioimpedance)

TypeobservationalSponsorUniversity of UtahRan2026 to 2027Enrolled25ConditionsMyelodysplastic Syndromes, Acute Myeloid LeukemiaArmsBioimpedance (BioZ)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elaine Wen-Ying WongDepartment of Electrical & Computer Engineering, The University of Utah, Salt Lake City, Utah, USA.
Sarbesh PandeyaDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Henry CrandallDepartment of Electrical & Computer Engineering, The University of Utah, Salt Lake City, Utah, USA.
Tristan SmartHuntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Madisen DixonDivision of Biostatistics, Huntsman Cancer Institute, The University of Utah, Salt Lake City, Utah, USA.
Kenneth M BoucherDivision of Biostatistics, Huntsman Cancer Institute, The University of Utah, Salt Lake City, Utah, USA.
Scott R FlorellDepartment of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Douglas GrossmanHuntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Benjamin SanchezDepartment of Electrical & Computer Engineering, The University of Utah, Salt Lake City, Utah, USA.

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
Electrical impedance dermography as a biomarker for basal and squamous cell carcinomaR21CA289101 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DOUGLAS GROSSMAN, Benjamin Sanchez Terrones · 2025 to 2026
$386k
NCATS NIH HHS UM1 TR004409NCI NIH HHS P30 CA042014NCI NIH HHS R21 CA289101
6 · The paper itself

Abstract

There are no currently available low-cost, noninvasive methods for discerning the depth of squamous cell carcinoma (SCC) invasion or distinguishing SCC from its benign mimics, such as inflamed seborrheic keratosis (SK). We studied 35 subjects with subsequently confirmed SCC or SK. Subjects underwent electrical impedance dermography measurements at six frequencies to assess the electrical properties of the lesion. Averaged greatest intrasession reproducibility values were 0.630 for invasive SCC at 128 kHz, 0.444 for SCC in situ at 16 kHz, and 0.460 for SK at 128 kHz. Electrical impedance dermography modeling revealed significant differences between SCC and inflamed SK in normal skin (

Identifiers

PMID37066115
PMCPMC10090659

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.