Evidence map›Paper›PMID 37066106›Full record

ReviewNeurology. Clinical practice2023

Imaging Spectrum of HTLV-1-Related Neurologic Disease: A Pooled Series and Review.

Luke Dixon, Cillian McNamara, Divya Dhasmana, Graham P Taylor, Nicholas Davies

Open access · hybridAbstract readReview
In one paragraph

Review in Neurology. Clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Luke DixonDepartment of Neuroradiology (LD, CM), Imperial College Healthcare NHS Trust, London, UK; National Centre for Human Retrovirology (DD, GPT, ND), Imperial College Healthcare NHS Trust, London, UK; Section of Virology, Department of Infectious Disease (GPT), Imperial College London, UK; Department of Neurology (GPT), Imperial College Healthcare NHS Trust, London, UK; Department of Neurology (GPT), Chelsea and Westminster Hospital NHS Trust, London, UK.
Cillian McNamaraDepartment of Neuroradiology (LD, CM), Imperial College Healthcare NHS Trust, London, UK; National Centre for Human Retrovirology (DD, GPT, ND), Imperial College Healthcare NHS Trust, London, UK; Section of Virology, Department of Infectious Disease (GPT), Imperial College London, UK; Department of Neurology (GPT), Imperial College Healthcare NHS Trust, London, UK; Department of Neurology (GPT), Chelsea and Westminster Hospital NHS Trust, London, UK.
Divya DhasmanaDepartment of Neuroradiology (LD, CM), Imperial College Healthcare NHS Trust, London, UK; National Centre for Human Retrovirology (DD, GPT, ND), Imperial College Healthcare NHS Trust, London, UK; Section of Virology, Department of Infectious Disease (GPT), Imperial College London, UK; Department of Neurology (GPT), Imperial College Healthcare NHS Trust, London, UK; Department of Neurology (GPT), Chelsea and Westminster Hospital NHS Trust, London, UK.
Graham P TaylorDepartment of Neuroradiology (LD, CM), Imperial College Healthcare NHS Trust, London, UK; National Centre for Human Retrovirology (DD, GPT, ND), Imperial College Healthcare NHS Trust, London, UK; Section of Virology, Department of Infectious Disease (GPT), Imperial College London, UK; Department of Neurology (GPT), Imperial College Healthcare NHS Trust, London, UK; Department of Neurology (GPT), Chelsea and Westminster Hospital NHS Trust, London, UK.
Nicholas DaviesDepartment of Neuroradiology (LD, CM), Imperial College Healthcare NHS Trust, London, UK; National Centre for Human Retrovirology (DD, GPT, ND), Imperial College Healthcare NHS Trust, London, UK; Section of Virology, Department of Infectious Disease (GPT), Imperial College London, UK; Department of Neurology (GPT), Imperial College Healthcare NHS Trust, London, UK; Department of Neurology (GPT), Chelsea and Westminster Hospital NHS Trust, London, UK.
Imperial College London · GBImperial College Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of Review: Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) is a well-recognized neurologic complication of HTLV-1. Beyond HAM, several other neurologic manifestations are increasingly recognized, including acute myelopathy, encephalopathy, and myositis. The clinical and imaging features of these presentations are less well understood and potentially underdiagnosed. In this study, we summarize the imaging features of HTLV-1-related neurologic disease, providing both a pictorial review and pooled series of the less well-recognized presentations. Recent Findings: 35 cases of acute/subacute HAM and 12 cases of HTLV-1-related encephalopathy were found. In subacute HAM, cervical and upper thoracic longitudinally extensive tranverse myelitis was noted, while in HTLV-1-related encephalopathy, confluent lesions in the frontoparietal white matter and along the corticospinal tracts were the most prevalent finding. Summary: There are varied clinical and imaging presentations of HTLV-1-related neurologic disease. Recognition of these features aids early diagnosis where therapy may have the greatest benefit.

Identifiers

PMID37066106
PMCPMC10092304
OpenAlexW4360991728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.