Evidence map›Paper›PMID 37065985›Full record

ArticleOpen forum infectious diseases2023

Longitudinal Neutralizing and Functional Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Variants Following Messenger RNA Coronavirus Disease 2019 Vaccination.

Xuemin Chen, Caroline Ciric, Theda Gibson, Larry J Anderson, Evan J Anderson, Christina A Rostad

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xuemin ChenDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Caroline CiricDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Theda GibsonDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Larry J AndersonDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Evan J AndersonDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Christina A RostadDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-8439-0592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this longitudinal prospective cohort of healthy adults in the United States, we found that coronavirus disease 2019 messenger RNA primary series and booster vaccinations elicited high titers of broadly cross-reactive neutralizing and antibody-dependent cell-mediated cytotoxicity antibodies, which gradually waned over 6 months, particularly against severe acute respiratory syndrome coronavirus 2 variants. These data support the indication for a subsequent booster vaccination.

Indexed as

ADCCantibody-dependent cell-mediated cytotoxicitydurabilityhybrid immunityOmicron

Identifiers

PMID37065985
PMCPMC10096895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.