Evidence map›Paper›PMID 37065631›Full record

ArticleJBMR plus2023

LRP6 High Bone Mass Characterized in Two Generations Harboring a Unique Mutation of Low-Density Lipoprotein Receptor-Related Protein 6.

Michael P Whyte, Steven Mumm, Jonathan C Baker, Fan Zhang, Homer Sedighi, Shenghui Duan, Tim Cundy

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Michael P WhyteDivision of Bone and Mineral Diseases, Department of Internal Medicine Washington University School of Medicine at Barnes-Jewish Hospital St. Louis MO USA.ORCID https://orcid.org/0000-0002-8755-8490
Steven MummDivision of Bone and Mineral Diseases, Department of Internal Medicine Washington University School of Medicine at Barnes-Jewish Hospital St. Louis MO USA.ORCID https://orcid.org/0000-0001-9267-4413
Jonathan C BakerMallinckrodt Institute of Radiology, Musculoskeletal Section Washington University School of Medicine St. Louis MO USA.
Fan ZhangCenter for Metabolic Bone Disease and Molecular Research Shriners Hospitals for Children - St. Louis St. Louis MO USA.
Homer SedighiDepartment of Plastic Surgery Washington University School of Medicine at St. Louis Children's Hospital St. Louis MO USA.
Shenghui DuanDivision of Bone and Mineral Diseases, Department of Internal Medicine Washington University School of Medicine at Barnes-Jewish Hospital St. Louis MO USA.
Tim CundyFaculty of Medical & Health Sciences University of Auckland Auckland New Zealand.ORCID https://orcid.org/0000-0003-4890-9400
Barnes-Jewish Hospital · USMallinckrodt (United States) · USShriners Hospitals for Children - St. Louis · USSt. Louis Children's Hospital · USUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoblast Wnt/

Indexed as

BONE DENSITYBONE MODELINGDICKKOPF1DXAENDOSTEUMEXOSTOSISHYPEROSTOSISHYPODONTIALOW‐DENSITY LIPOPROTEIN RECEPTOR‐RELATED PROTEINLRP4LRP5LRP6METABOLIC BONE DISEASEOLIGODONTIAOSTEOBLASTOSTEOGENESISOSTEOPETROSISOSTEOSCLEROSISSCLEROSTINSKELETAL DYSPLASIASOSTTORUS PALATINUSWNTΒ‐CATENIN

Identifiers

PMID37065631
PMCPMC10097642
OpenAlexW4315645751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.