ArticleFrontiers in aging neuroscience2023
Evaluation of a novel scoring system based on thrombosis and inflammation for predicting stroke-associated pneumonia: A retrospective cohort study.
Article in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 7 citations in OpenAlex.
- From Stroke to Infection: The Emerging Role of Fibrinogen-to-Albumin Ratio in Predicting Stroke-Associated Pneumonia.Cureus · 2025Article
- Evaluation of the Wells score in predicting the incidence of stroke-associated pneumonia: the REMISE study.Frontiers in neurology · 2025Article
- Association between cumulative changes in the Wells score and the risk of stroke-associated pneumonia in patients with acute ischemic stroke: results from the REMISE study.Frontiers in neurology · 2025Article
- Thrombo-inflammatory prognostic score can predict the outcome of stroke: a retrospective cohort study.Frontiers in aging neuroscience · 2024Article
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10 authors at 2 institutions in 1 country.
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Abstract
Background: Inflammation and thrombosis are involved in the development of stroke-associated pneumonia (SAP). Our aim was to evaluate the predictive value of a novel, simplified, thrombo-inflammatory prognostic score (TIPS) that combines both inflammatory and thrombus biomarkers in the early phase of ischemic stroke (IS). Methods: The study population consisted of 897 patients with a first diagnosis of IS admitted to the emergency department of five tertiary hospitals in China. Of these, the data from 70% of patients was randomly selected to derive the model and the other 30% for model validation. A TIPS of "2" was indicative of high inflammation and thrombosis biomarkers and "1" of one biomarker, with "0" indicative of absence of biomarkers. Multivariate logistic regression analyses were used to identify the association between TIPS and SAP. Results: The TIPS was an independent predictor of SAP and 90-day mortality, with the incidence of SAP being significantly higher for patients with a high TIPS. The TIPS provided superior predictive value for SAP than clinical scores (A Conclusion: The TIPS score may be a useful tool for early identification of patients at high-risk for SAP after IS.
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