ArticleFrontiers in oral health2023
Dynamics of oral microbiome acquisition in healthy infants: A pilot study.
Article in Frontiers in oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Maternal influences on oral microbiome development and implications for early childhood health: a systematic review.Infection and immunity · 2026Pooled it
- Ultrasmall oral Saccharibacteria modulate gingival immunoactivation through type IV pili and TLR2-dependent endocytosis.Nature communications · 2026Article
- Concentrations of selected human milk components influence the infant oral microbiome to a greater degree than estimated intakes.Frontiers in cellular and infection microbiology · 2026Article
- Development of the Breastfed Infant Oral Microbiome Is Associated with Concentrations and Intakes of Human Milk Oligosaccharides.Nutrients · 2025Article
- The impact of very low birth weight on children's oral health in adolescence.Scientific reports · 2025Article
- The Infant Oral Microbiome: Developmental Dynamics, Modulating Factors, and Implications for Oral and Systemic Health.International journal of molecular sciences · 2025Review
- A Comparative Analysis of Feeding Practices and Oral Immunity in Infants.Medicina (Kaunas, Lithuania) · 2025Article
- First-year dynamics of the anaerobic microbiome and archaeome in infants' oral and gastrointestinal systems.mSystems · 2025Article
- Development of the breastfed infant oral microbiome over the first two years of life in the BLOSOM Cohort.Frontiers in cellular and infection microbiology · 2025Article
- Review
- Oral Microbiota: The Influences and Interactions of Saliva, IgA, and Dietary Factors in Health and Disease.Microorganisms · 2023Review
- Impact of breastfeeding and other early-life factors on the development of the oral microbiome.Frontiers in microbiology · 2023Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Objectives: The human oral microbiota is one of the most complex bacterial communities in the human body. However, how newborns initially acquire these bacteria remains largely unknown. In this study, we examined the dynamics of oral microbial communities in healthy infants and investigated the influence of the maternal oral microbiota on the acquisition of the infant's oral microbiota. We hypothesized that the infant oral microbial diversity increases with age. Methods: One hundred and sixteen whole-salivary samples were collected from 32 healthy infants and their biological mothers during postpartum and 9- and 15-month well-infant visits. Bacterial genomic DNA was extracted and sequenced by Human Oral Microbe Identification using Next Generation Sequencing (HOMI Results: A total of 6,870,571 16S rRNA reads were generated from paired mother-infant saliva samples. Overall, oral microbial profiles significantly differed between the mother and infant groups ( Conclusions: This study provides new evidence that the oral cavities of infants are colonized by a distinct group of bacterial species at birth. The acquisition and diversity of changes in oral microbial composition are dynamic during the first year of an infant's life. Before reaching the second birthday, the composition of the oral microbial community could be more similar to that of their biological mothers.
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