Evidence map›Paper›PMID 37065356›Full record

ArticleCureus2023

Dubin-Johnson Syndrome: A Case Report.

Abdul Hannan Siddiqui, Muhammad R Alsabe, Zuha Tehseen, Modather I Hatamleh, Sanzida Taslim, Ameer Abdelrahman, Faraz Saleem

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Risk Assessment for Drug-Induced Hyperbilirubinemia: A Mechanistic Approach.CPT: pharmacometrics & systems pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Abdul Hannan SiddiquiInternal Medicine, University Hospital Derby and Burton, Derby, GBR.
Muhammad R AlsabeMedicine, Ross University School of Medicine, Queens, USA.
Zuha TehseenInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, California, USA.
Modather I HatamlehInternal Medicine, King Abdullah bin Abdulaziz University Hospital, Amman, JOR.
Sanzida TaslimInternal Medicine, Ross University School of Medicine, Far Rockaway, USA.
Ameer AbdelrahmanMedicine, Inova Alexandria Hospital, Virginia, USA.
Faraz SaleemInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, California, USA.
Queens University · BDUniversity of Derby · GBInova Alexandria Hospital · USRockaway Waterfront Alliance · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dubin-Johnson syndrome (DJS) is a rare autosomal recessive genetic disease caused by mutations in the bilirubin transporter MRP2. It is characterized by recurrent episodes of jaundice and conjugated hyperbilirubinemia. Numerous instances of hyperbilirubinemia disorders resembling Dubin-Johnson syndrome have been documented, but they differ in the clinical presentation, amount of conjugated bilirubin present, and their reaction to therapy. Most people with this syndrome do not have any symptoms, so their cases are often misdiagnosed and not properly taken care of. Here, we present a case of a teenage male patient who complained of recurring jaundice and abdominal pain. Further examination and testing revealed that the patient had been jaundiced since birth and had a family history of the condition. Conservative management was implemented, and follow-up demonstrated a positive prognosis. This case is a rare example of Dubin-Johnson syndrome, although patients with the condition generally have a normal life expectancy and only require conservative management.

Indexed as

#conjugated hyperbilirubinemiadjsdubin jhonson syndrome#hyperbilirubinemia#liver#liver abnormalitiesliver histopathology

Identifiers

PMID37065356
PMCPMC10099096
OpenAlexW4324143669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.