Evidence map›Paper›PMID 37065281›Full record

ReviewCureus2023

Sleep Disorders in Mild Cognitive Impairment.

Bhawna Randhi, Sai Dheeraj Gutlapalli, Jingxiong Pu, Maheen F Zaidi, Maithily Patel, Lakshmi Malvika Atluri, Natalie A Gonzalez, Navya Sakhamuri, Sreekartthik Athiyaman, Pousette Hamid

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Management of MCI in the Outpatient Setting.Current psychiatry reports · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 5 countries.

Bhawna RandhiMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sai Dheeraj GutlapalliInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Jingxiong PuPsychiatry and Behavioral Sciences, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Maheen F ZaidiResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Maithily PatelFamily Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Lakshmi Malvika AtluriSurgery, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Natalie A GonzalezPediatrics, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Navya SakhamuriInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sreekartthik AthiyamanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Pousette HamidNeurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · USMayo Clinic · USMedical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have an increasingly aging population and, therefore, cognitive impairment and dementia are becoming more common. Similarly, sleep disorders are also more common among the older population. There is a bidirectional relationship between mild cognitive impairment and sleep disorders. Additionally, both of these issues are underdiagnosed. By identifying and treating sleep disturbances early, we may delay the onset of dementia. Sleep helps in clearing metabolites like amyloid-beta (A-beta) lipoprotein. Clearance leads to decreased fatigue and proper functioning of the brain. A-beta lipoprotein and tau aggregates lead to neurodegeneration. Slow-wave sleep that decreases with aging is important for memory consolidation. In the initial stages of Alzheimer's disease, A-beta lipoprotein and tau deposits were linked to lower slow-wave activity in non-rapid eye movement sleep. Improvement in sleep decreases oxidative stress which in turn leads to decreased A-beta lipoprotein accumulation.

Indexed as

aging populationalzheimer’s dementiacognitive impairment and dementiamemory consolidationsleep disorderssleep therapiesslow wave activity

Identifiers

PMID37065281
PMCPMC10103826
OpenAlexW4324319571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.