Evidence map›Paper›PMID 37065168›Full record

ArticleRespirology case reports2023

Rapidly progressive respiratory failure due to antisynthetase syndrome related interstitial lung disease.

Marwan Almubarek, Darryl P Boy, Usha Lalla, Brian W Allwood, Elvis M Irusen, Coenraad F N Koegelenberg

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marwan AlmubarekDivision of Pulmonology, Department of Medicine Stellenbosch University & Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0003-1206-7459
Darryl P BoyDivision of Pulmonology, Department of Medicine Stellenbosch University & Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0002-0620-9775
Usha LallaDivision of Pulmonology, Department of Medicine Stellenbosch University & Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0002-4395-5152
Brian W AllwoodDivision of Pulmonology, Department of Medicine Stellenbosch University & Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0003-0421-2978
Elvis M IrusenDivision of Pulmonology, Department of Medicine Stellenbosch University & Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0002-2134-3251
Coenraad F N KoegelenbergDivision of Pulmonology, Department of Medicine Stellenbosch University & Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0002-5563-8429
Stellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old female was admitted with rapidly progressive respiratory failure requiring intubation and mechanical ventilation. She was considered to have an infective exacerbation of underlying interstitial lung disease (ILD). She improved on antibiotics, but the interstitial process progressed rapidly, and she could not be weaned. An antimyositis antibody panel yielded a strongly positive anti-Jo-1 and anti-Ro 52. A diagnosis of antisynthetase syndrome (ASS) associated ILD, a very rare disease with high mortality, was made. She was managed with high-dose corticosteroids and intravenous immunoglobulin therapy and was eventually liberated from mechanical ventilation. This case highlights the importance of considering ASS in an otherwise unexplained rapidly progressive ILD requiring mechanical ventilation.

Indexed as

anti‐Jo‐1 antibodyanti‐Ro52 antibodyantisynthetase syndromeinterstitial lung diseaseintravenous immunoglobulin

Identifiers

PMID37065168
PMCPMC10098056
OpenAlexW4365455804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.