Evidence map›Paper›PMID 37065022›Full record

ArticleACS omega2023

Discovery of Novel Dimeric Pyridinium Bromide Analogues Inhibits Cancer Cell Growth by Activating Caspases and Downregulating Bcl-2 Protein.

Senthilnathan Govindaraj, Kilivelu Ganesan, Mahendiran Dharmasivam, Lakshmisundaram Raman, Kalaivani M Kuppusamy, Viswanathan Pandiappan, Mohammed Mujahid Alam, Amanullah Mohammed

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Senthilnathan GovindarajPG and Research Department of Chemistry, Presidency College, Chennai 600005, India.
Kilivelu GanesanPG and Research Department of Chemistry, Presidency College, Chennai 600005, India.ORCID https://orcid.org/0000-0003-2127-4388
Mahendiran DharmasivamCentre for Cancer Cell Biology and Drug Discovery, Griffith Institute for Drug Discovery, Griffith University, Nathan, Brisbane, Queensland 4111, Australia.
Lakshmisundaram RamanSri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Educational and Research (DU), Porur, Chennai 600116, India.
Kalaivani M KuppusamyResearch Centre for Cellular Genomics and Cancer Research, Sree Balaji Medical College and Hospital, Chennai 600044, India.
Viswanathan PandiappanDepartment of Uyivedhiyal, JSA Medical College for Siddha and Research Centre, Ulundurpet, Kallakkurichi 606 104, India.
Mohammed Mujahid AlamDepartment of Chemistry, College of Science, King Khalid University, PO Box 9004, Abha 61413, Kingdom of Saudi Arabia.
Amanullah MohammedDepartment of Clinical Biochemistry, College of Medicine, King Khalid University, Abha 61413, Kingdom of Saudi Arabia.
King Khalid University · SAPresidency University · INDhanvantari Ayurveda College Hospital and Research Centre · INGriffith University · AUSree Balaji Dental College and Hospital · INSri Ramachandra Institute of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flexible dimeric substituted pyridinium bromides with primary and tertiary amines are prepared by conventional and solvent-free methods. The formation of compounds

Identifiers

PMID37065022
PMCPMC10099142
OpenAlexW4361001254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.