Evidence map›Paper›PMID 37064902›Full record

ArticleFrontiers in physiology2023

Chronic environmental circadian disruption increases atherosclerosis and dyslipidemia in female, but not male,

Jeffrey M Chalfant, Deborah A Howatt, Victoria B Johnson, Lisa R Tannock, Alan Daugherty, Julie S Pendergast

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Estrogen signaling is necessary for the sex difference in simulated jet lag in mice.American journal of physiology. Endocrinology and metabolism · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeffrey M ChalfantDepartment of Biology, University of Kentucky, Lexington, KY, United States.
Deborah A HowattSaha Cardiovascular Research Center, University of Kentucky, Lexington, KY, United States.
Victoria B JohnsonDepartment of Biology, University of Kentucky, Lexington, KY, United States.
Lisa R TannockSaha Cardiovascular Research Center, University of Kentucky, Lexington, KY, United States.
Alan DaughertySaha Cardiovascular Research Center, University of Kentucky, Lexington, KY, United States.
Julie S PendergastDepartment of Biology, University of Kentucky, Lexington, KY, United States.
University of Kentucky · US

Funding

The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2012 to 2017
$13.7M
Pilot Projects ProgramP30GM127211 · NIGMS · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2018 to 2022
$5.7M
Feasibility of implementing time-restricted eating in women with mild cognitive impairmentR01DK124774 · NIDDK · UNIVERSITY OF KENTUCKY · PI PENDERGAST, JULIE S · 2021 to 2025
$3.3M
NIDDK NIH HHS R01 DK124774NIGMS NIH HHS P20 GM103527NIGMS NIH HHS P30 GM127211
6 · The paper itself

Abstract

Shift work chronically disrupts circadian rhythms and increases the risk of developing cardiovascular disease. However, the mechanisms linking shift work and cardiovascular disease are largely unknown. The goal of this study was to investigate the effects of chronically shifting the light-dark (LD) cycle, which models the disordered exposure to light that may occur during shift work, on atherosclerosis. Atherosclerosis is the progressive accumulation of lipid-filled lesions within the artery wall and is the leading cause of cardiovascular disease. We studied

Indexed as

cardiovascular diseasecircadian rhythmeating rhythmfastingshift work

Identifiers

PMID37064902
PMCPMC10090465
OpenAlexW4361201362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.