Evidence map›Paper›PMID 37064878›Full record

ArticleTheranostics2023

Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.

Bojun Li, Yuqi Xia, Shuqin Mei, Zehua Ye, Baofeng Song, Xinzhou Yan, Fangyou Lin, Ting Rao, Weimin Yu, Changlin Mei and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Review
  6. Article
  7. Review
  8. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  9. Article
  10. Article
  11. Knockdown of SOX4 attenuates sepsis myocardial injury by inhibiting the EZH2/H3K27me3/SOCS3 axis.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. MiR-26a-5p/EZH2 Mediates Wnt2 Promoter Methylation to Regulate Trophoblast Dysfunction.Combinatorial chemistry & high throughput screening · 2026
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Bojun LiDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Yuqi XiaDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Shuqin MeiDepartment of Nephrology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Zehua YeDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Baofeng SongDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Xinzhou YanDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Fangyou LinDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Ting RaoDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Weimin YuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Changlin MeiDepartment of Nephrology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Jiayi LvDepartment of Nephrology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Ming WuDepartment of Nephrology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Zhiguo MaoDepartment of Nephrology, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Xiangjun ZhouDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Fan ChengDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Renmin Hospital of Wuhan University · CNShanghai Changzheng Hospital · CNWuhan University · CNShuguang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Kidney InjuryEnhancer of Zeste Homolog 2 ProteinSepsisAnimalsApoptosisbeta CateninHistone MethyltransferasesHistonesInflammationLipopolysaccharidesMiceMice, Knockoutbeta CateninEnhancer of Zeste Homolog 2 ProteinEzh2 protein, mouseHistone MethyltransferasesHistonesLipopolysaccharidesAcute kidney injuryEpigeneticEZH2Inflammationsepsis

Identifiers

PMID37064878
PMCPMC10091874
OpenAlexW4364321697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.