Evidence map›Paper›PMID 37064511›Full record

ArticleEClinicalMedicine2023

Magnetic resonance imaging reference values for cardiac morphology, function and tissue composition in adolescents.

Carlos Real, Rocío Párraga, Gonzalo Pizarro, Inés García-Lunar, Ernesto González-Calvo, Jesús Martínez-Gómez, Javier Sánchez-González, Patricia Sampedro, Irene Sanmamed, Mercedes De Miguel and 6 more

Open access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Society for Cardiovascular Magnetic Resonance reference values ("normal values") in cardiovascular magnetic resonance: 2025 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  2. Age-, body surface area-, and sex-specific reference values for cardiovascular magnetic resonance imaging derived ventricular and atrial size and function for Chinese healthy children.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Pooled it
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  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Carlos RealCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Rocío PárragaCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Gonzalo PizarroCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Inés García-LunarCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Ernesto González-CalvoCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Jesús Martínez-GómezCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Javier Sánchez-GonzálezPhilips Healthcare Spain, Madrid, Spain.
Patricia SampedroCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Irene SanmamedCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Mercedes De MiguelCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Amaya De Cos-GandoyCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Patricia BodegaCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Borja IbanezCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Gloria Santos-BeneitFoundation for Science, Health and Education (SHE), Barcelona, Spain.
Valentin FusterCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Rodrigo Fernández-JiménezCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
Spanish National Centre for Cardiovascular Research · ESCardiovascular Institute of the South · USPhilips (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular magnetic resonance (CMR) is a precise tool for the assessment of cardiac anatomy, function, and tissue composition. However, studies providing CMR reference values in adolescence are scarce. We aim to provide sex-specific CMR reference values for biventricular and atrial dimensions and function and myocardial relaxation times in this population. Methods: Adolescents aged 15-18 years with no known cardiovascular disease underwent a non-contrast 3-T CMR scan between March 2021 and October 2021. The imaging protocol included a cine steady-state free-precession sequence for the analysis of chamber size and function, as well as T2-GraSE and native MOLLI T1-mapping for the characterization of myocardial tissue. Findings: CMR scans were performed in 123 adolescents (mean age 16 ± 0.5 years, 52% girls). Mean left and right ventricular end-diastolic indexed volumes were higher in boys than in girls (91.7 ± 11.6 vs 78.1 ± 8.3 ml/m Interpretation: This cross-sectional study provides overall and sex-stratified CMR reference values for cardiac dimensions and function, and myocardial tissue properties, in adolescents. This information is useful for clinical practice and may help in the differential diagnosis of cardiac diseases, such as cardiomyopathies and myocarditis, in this population. Funding: Instituto de Salud Carlos III (PI19/01704).

Indexed as

AdolescentDifferential diagnosisMagnetic resonancePediatricsReference valuesVentricular function

Identifiers

PMID37064511
PMCPMC10102894
OpenAlexW4323043239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.