Evidence map›Paper›PMID 37064431›Full record

ReviewDrug design, development and therapy2023

Celastrol: A Potential Natural Lead Molecule for New Drug Design, Development and Therapy for Memory Impairment.

Muhamad Azrul Amir Yusri, Mahendran Sekar, Ling Shing Wong, Siew Hua Gan, Subban Ravi, Vetriselvan Subramaniyan, Nur Najihah Izzati Mat Rani, Kumarappan Chidambaram, M Yasmin Begum, Mohankumar Ramar and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in Drug design, development and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 4 countries.

Muhamad Azrul Amir YusriDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Perak, Malaysia.
Mahendran SekarSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Subang Jaya, Selangor, Malaysia.ORCID 0000-0002-3022-6137
Ling Shing WongFaculty of Health and Life Sciences, INTI International University, Nilai, Malaysia.ORCID 0000-0002-5869-0804
Siew Hua GanSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Subang Jaya, Selangor, Malaysia.ORCID 0000-0001-6470-3651
Subban RaviDepartment of Chemistry, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, India.
Vetriselvan SubramaniyanJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Nur Najihah Izzati Mat RaniFaculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Perak, Malaysia.
Kumarappan ChidambaramDepartment of Pharmacology, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-7981-4562
M Yasmin BegumDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-1871-8585
Mohankumar RamarDepartment of Surgical Research, Rhode Island Hospital, Alpert Medical School, Brown University, Providence, RI, USA.ORCID 0000-0003-2047-9808
Sher Zaman SafiFaculty of Medicine, Bioscience and Nursing, MAHSA University, Bandar Saujana Putra, Jenjarom, Selangor, Malaysia.
Siddharthan SelvarajFaculty of Dentistry, AIMST University, Bedong, Kedah, Malaysia.ORCID 0000-0002-7776-3335
Yuan Seng WuDepartment of Biological Sciences and Centre for Virus and Vaccine Research, School of Medical and Life Sciences, Sunway University, Subang Jaya, Selangor, Malaysia.ORCID 0000-0001-5574-8049
Palanisamy RevathyDepartment of Computer Applications, Gobi Arts & Science College, Gobichettipalayam, Tamil Nadu, India.
Shivkanya FuloriaFaculty of Pharmacy, AIMST University, Bedong, Kedah, Malaysia.
Neeraj Kumar FuloriaFaculty of Pharmacy, AIMST University, Bedong, Kedah, Malaysia.
Pei Teng LumDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Perak, Malaysia.
Sinouvassane DjearamaneDepartment of Biomedical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, Perak, Malaysia.
AIMST University · MYMonash University Malaysia · MYUniversity of Kuala Lumpur · MYKing Khalid University · SABrown University · USINTI International University · MYKarpagam Academy of Higher Education · INMahsa University · MYSunway University · MYUniversiti Tunku Abdul Rahman · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celastrol is a naturally occurring chemical isolated from

Indexed as

TriterpenesAnimalsDrug DesignOxidative StressPentacyclic TriterpenescelastrolPentacyclic TriterpenesTriterpenescelastroldrug discoverymemory impairmentnatural productsneuroprotection

Identifiers

PMID37064431
PMCPMC10093558
OpenAlexW4362697457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.