Evidence map›Paper›PMID 37064239›Full record

ReviewFrontiers in bioengineering and biotechnology2023

The function of immunomodulation and biomaterials for scaffold in the process of bone defect repair: A review.

Changchao Dong, Gang Tan, Guangyan Zhang, Wei Lin, Guanglin Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Osteogenic Potential of 3D-Printed Porous Poly(lactide-ACS applied materials & interfaces · 2025
    Article
  9. Review
  10. Injectable organic-inorganic hybrid hydrogels for bone defect repair.Frontiers in bioengineering and biotechnology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Comparison of different hydroxyapatite composites for bone tissue repair:Iranian journal of basic medical sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Changchao DongTrauma Medical Center, Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Gang TanDepartment of Orthopedics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Guangyan ZhangDepartment of Respiratory Medicine, The 7th Hospital of Chengdu, Chengdu, Sichuan, China.
Wei LinDepartment of Gynecology, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China.
Guanglin WangTrauma Medical Center, Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
West China Hospital of Sichuan University · CNSichuan University · CNThe Eighth Hospital of Xi'an · CNWest China Second University Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process of bone regeneration involves the interaction of the skeletal, blood, and immune systems. Bone provides a solid barrier for the origin and development of immune cells in the bone marrow. At the same time, immune cells secrete related factors to feedback on the remodeling of the skeletal system. Pathological or traumatic injury of bone tissue involves changes in blood supply, cell behavior, and cytokine expression. Immune cells and their factors play an essential role in repairing foreign bodies in bone injury or implantation of biomaterials, the clearance of dead cells, and the regeneration of bone tissue. This article reviews the bone regeneration application of the bone tissue repair microenvironment in bone cells and immune cells in the bone marrow and the interaction of materials and immune cells.

Indexed as

biomaterialsBMSCsbone regenerationimmune cellsinteraction

Identifiers

PMID37064239
PMCPMC10090379
OpenAlexW4361289760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.