Evidence map›Paper›PMID 37064209›Full record

ArticleFrontiers in neurology2023

INPH and parkinsonism: A positive shunt response with a negative tap test.

Giulia Giannini, Ignacio Jusue-Torres, Paolo Mantovani, Liliana Mazza, Alessandro Pirina, Nicola Valsecchi, David Milletti, Luca Albini-Riccioli, Sabina Cevoli, Sevil Yasar and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Implications of the glymphatic system in the diagnostic and surgical workup of normal pressure hydrocephalus.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  4. Long-term gait improvement following a CSF tap test in idiopathic normal pressure hydrocephalus patients: an analysis of clinical outcomes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Giulia GianniniUnit of Neurology, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Ignacio Jusue-TorresDepartment of Neurological Surgery, Mayo Clinic, Rochester, MN, United States.
Paolo MantovaniUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Liliana MazzaDipartimento dell'Integrazione Geriatria, Ospedale Maggiore, AUSL Bologna, Bologna, Italy.
Alessandro PirinaUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Nicola ValsecchiUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
David MillettiUnit of Rehabilitation Medicine, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Luca Albini-RiccioliUnit of Neuroradiology, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Sabina CevoliUnit of Neurology, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Sevil YasarDivision of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Giorgio PalandriUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Istituto delle Scienze Neurologiche di Bologna · ITJohns Hopkins University · USOspedale Maggiore · ITWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The aim of this study was to compare clinical and functional performances of idiopathic normal pressure hydrocephalus (INPH) patients with and without parkinsonism at the initial evaluation, 72 h after the cerebrospinal fluid tap test (CSF TT), and 6 months after ventriculoperitoneal shunt (VPS) surgery. Materials and methods: This is an observational prospective study on patients with INPH who underwent VPS. Patients were classified into INPH with parkinsonism (INPH-P Results: A total of 64 patients with probable INPH were included, 12 patients with INPH-P Conclusion: Patients with INPH and parkinsonism overall do worse than patients without parkinsonism. An unsatisfying response to the CSF tap test in INPH patients with parkinsonism should not be used as an exclusion criterion from VPS surgery since patients with and without parkinsonism showed significant improvement post-VPS.

Indexed as

cohort studynormal pressure hydrocephalusparkinsonismshunttap test

Identifiers

PMID37064209
PMCPMC10090367
OpenAlexW4361291281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.