Evidence map›Paper›PMID 37064207›Full record

ArticleFrontiers in neurology2023

Prescription trends of antiseizure medications before and during the COVID-19 pandemic.

Alekhya Lavu, Donica Janzen, Laila Aboulatta, Payam Peymani, Lara Haidar, Brianne Desrochers, Silvia Alessi-Severini, Sherif Eltonsy

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alekhya LavuCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Donica JanzenCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Laila AboulattaCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Payam PeymaniCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Lara HaidarCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Brianne DesrochersCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Silvia Alessi-SeveriniCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
Sherif EltonsyCollege of Pharmacy, University of Manitoba, Winnipeg, MB, Canada.
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Given the lack of evidence on how the COVID-19 pandemic impacted antiseizure medication (ASM) use, we examined the trends of ASMs before and during COVID-19. Methods: We conducted a population-based study using provincial-level health databases from Manitoba, Canada, between 1 June 2016 and 1 March 2021. We used interrupted time series autoregressive models to examine changes in the prevalence and incidence of ASM prescription rates associated with COVID-19 public health restrictions. Results: Among prevalent users, the COVID-19 pandemic led to a significant increase in new-generation ASMs with a percentage change of 0.09% ( Conclusion: With the introduction of public health measures during COVID-19, small but significant changes in the incident and prevalent use of ASM prescriptions were observed. Further studies are needed to examine whether barriers to medication access were associated with potential deterioration in seizure control among patients. Conference presentation: The results from this study have been presented as an oral presentation at the 38th ICPE, International Society of Pharmacoepidemiology (ISPE) annual conference in Copenhagen.

Indexed as

antiepileptic drugsantiseizure medicationsCOVID-19drug utilizationepilepsyprescription patternsseizures

Identifiers

PMID37064207
PMCPMC10101333
OpenAlexW4361275487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.