ArticleFrontiers in oncology2023
Prognostic role of preoperative inflammatory markers in postoperative patients with colorectal cancer.
Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Periprocedural Changes of Serum Biomarkers in Predicting Complications Following Bariatric Surgery for Obesity: Systematic Review and Meta-analysis.Obesity surgery · 2024Pooled it
- Machine learning to predict ureteral access sheath placement failure in flexible ureteroscopy: development and prospective validation.BMC urology · 2026Article
- Triglyceride-to-glucose index and lymphocyte-to-monocyte ratio enhance prognostic accuracy for colorectal cancer patients: a multicenter machine learning cohort study.Translational cancer research · 2026Article
- Prognostic Value of Albumin-to-CEA Ratio in Metastatic Colorectal Cancer: A Retrospective Study.Biomedicines · 2026Article
- Association of dynamic platelet-to-lymphocyte ratio trajectories using group-based trajectory modeling with short-term outcomes and survival in patients undergoing laparoscopic radical resection for rectal cancer: a retrospective study.Frontiers in oncology · 2026Article
- Preoperative albumin to carcinoembryonic antigen ratio predicts clinicopathological features and survival in colorectal cancer: a prognostic nomogram study.Frontiers in oncology · 2026Article
- Article
- Metformin Inhibits NLRP3 Inflammasome Expression and Regulates Inflammatory Microenvironment to Delay the Progression of Colorectal Cancer.Recent patents on anti-cancer drug discovery · 2025Article
- The Preoperative C-reactive Protein/Albumin Ratio of Immune-inflammation Index Is an Independent Prognostic Factor of Advanced Colorectal Cancer in Older Patients (≥ 65 years).Journal of the anus, rectum and colon · 2025Article
- Prognostic value of neutrophil-to-lymphocyte ratios pre- and post-surgery in stage III CRC: a study of 2,742 patients.International journal of colorectal disease · 2024Article
- Red Cell Distribution Width as a Predictor of Survival in Patients with Hepatocellular Carcinoma.Medicina (Kaunas, Lithuania) · 2024Article
- Prognostic value of preoperative combined with postoperative systemic immune-inflammation index for disease-free survival after radical rectal cancer surgery: a retrospective cohort study.Translational cancer research · 2024Article
- GLR in Colorectal Cancers: An Easily Accessible Prognostic Marker.International journal of general medicine · 2024Article
- Association of Complete Blood Cell Count-Derived Inflammatory Biomarkers with Psoriasis and Mortality.Clinical, cosmetic and investigational dermatology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Inflammatory response markers are prognostic factors for several cancers, but their role in postoperative colorectal cancer (CRC) is unclear. The purpose was to evaluate the role of preoperative Neutrophil-to-Lymphocyte ratio (NLR), Platelet-to-Lymphocyte-ratio (PLR), and Lymphocyte-to-Monocyte ratio (LMR) in the prognosis of postoperative CRC patients. Methods: We retrospectively reviewed 448 CRC patients who had undergone surgical resection from December 2015 to December 2017 in our hospital. The plasma NLR, PLR, LMR, CEA, and CA19-9 were collected within 2 weeks before the operation. We recorded the clinical characteristics and survival data by reviewing medical records and phone calls. We analyzed preoperative inflammatory markers and clinical features using Pearson chi-squared tests or Fisher's tests. Uni- and multivariate Cox regression analyses were performed, and overall survival (OS) was estimated with the Kaplan-Meier method. Results: High NLR and PLR were associated with worse overall survival in postoperative CRC (HR = 2.140, 95%CI = (1.488-3.078), Conclusion: Current evidence indicates that preoperative inflammatory markers NLR, LMR, and PLR are associated with overall survival in postoperative patients with colorectal cancer. NLR is an independent risk factor, and LMR is an independent protective factor in CRC patients after surgery.
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