Evidence map›Paper›PMID 37064047›Full record

ArticleSouthern African journal of HIV medicine2023

The prevalence of cervical abnormalities: Comparison of youth with perinatally acquired HIV and older women in Botswana.

Thabo Phologolo, Mogomotsi Matshaba, Bathusi Mathuba, Keboletse Mokete, Ontibile Tshume, Elizabeth Lowenthal

Open access · goldAbstract read
In one paragraph

Article in Southern African journal of HIV medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Thabo PhologoloDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.ORCID https://orcid.org/0000-0001-9061-3510
Mogomotsi MatshabaBotswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana.ORCID https://orcid.org/0000-0002-6441-1218
Bathusi MathubaBotswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana.ORCID https://orcid.org/0000-0003-0925-0586
Keboletse MoketeBotswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana.ORCID https://orcid.org/0000-0002-7531-4085
Ontibile TshumeBotswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana.ORCID https://orcid.org/0000-0003-1635-6215
Elizabeth LowenthalDepartments of Pediatrics and Epidemiology, Biostatistics and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America.ORCID https://orcid.org/0000-0002-3855-8646
Botswana-Baylor Children's Clinical Center of Excellence · BWUniversity of Botswana · BWUniversity of Pennsylvania · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
HIV Research Training Program for BotswanaD43TW009781 · FIC · UNIVERSITY OF PENNSYLVANIA · PI GROSS, ROBERT · 2014 to 2018
$1.7M
FIC NIH HHS D43 TW009781NIAID NIH HHS P30 AI045008
6 · The paper itself

Abstract

Background: Cervical cancer burden and prevalence of precursor lesions is unknown among young women living with HIV in high prevalence settings. Current cervical cancer screening guidelines in resource-limited settings with high HIV prevalence typically exclude adolescents and young women. After observing two cases of advanced cervical cancer among young women with perinatally acquired HIV, a pilot screening programme was established in Botswana. Objectives: To compare the prevalence of cervical abnormalities in young women with perinatally acquired HIV with women aged 30-49 years, regardless of HIV status. Method: We conducted a cross-sectional study of 30-49-year-old women who had visual inspection with acetic acid screening through the Botswana public sector programme, and youth (aged 15-24 years) with perinatally acquired HIV, at a single referral site between 2016 and 2018. We describe the prevalence of cervical abnormalities in each group as well as the crude prevalence ratio. Results: The prevalence of cervical abnormalities in women 30-49 years of age was 10.9% (95% confidence interval [CI]: 10.4, 11.4), and 10.1% (95% CI: 4.7, 18.3) for youth. The crude prevalence ratio was 1.07 (95% CI: 0.58, 2.01). Conclusion: Inclusion of youth living with HIV in cervical cancer screening services should be considered in settings with a high prevalence of HIV and cervical cancer.

Indexed as

Africacervical cancer screeningperinatal HIVvisual inspection with acetic acidyoung women

Identifiers

PMID37064047
PMCPMC10091167
OpenAlexW4362584515

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.