Evidence map›Paper›PMID 37063979›Full record

ArticleJournal of oral microbiology2023

Profiles of oral microbiome associated with nasogastric tube feeding.

Ding-Han Wang, Fa-Tzu Tsai, Hsi-Feng Tu, Cheng-Chieh Yang, Ming-Lun Hsu, Lin-Jack Huang, Chiu-Tzu Lin, Wun-Eng Hsu, Yu-Cheng Lin

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ding-Han WangDepartment of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0003-3314-6113
Fa-Tzu TsaiDepartment of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-0468-2614
Hsi-Feng TuDepartment of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0003-0177-6065
Cheng-Chieh YangDepartment of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-5355-0087
Ming-Lun HsuDepartment of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0001-6753-0485
Lin-Jack HuangDepartment of Dentistry, National Yang Ming Chiao Tung University Hospital, Yilan County, Taiwan.
Chiu-Tzu LinDepartment of Dentistry, National Yang Ming Chiao Tung University Hospital, Yilan County, Taiwan.
Wun-Eng HsuDepartment of Dentistry, Far Eastern Memorial Hospital, New Taipei, Taiwan.
Yu-Cheng LinDepartment of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-4787-2565
National Yang Ming Chiao Tung University · TWFar Eastern Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dysbiosis of oral microbiome causes chronic diseases including dental caries and periodontitis, which frequently affect older patient populations. Severely disabled individuals with impaired swallowing functions may require nutritional supply via nasogastric (NG) tubes, further impacting their oral condition and possibly microbial composition. However, little is known about the effect of NG tube on oral microbes and its potential ramification. Methods: By using 16S rRNA amplicon sequencing, we characterized the tongue microbiome of 27 patients fed with NG tubes and 26 others fed orally. Results: The microbial compositions of NG-tube and oral-feeding patients were substantially different, with more Gram-negative aerobes enriched in the presence of NG tube. Specifically, NG-tube patients presented more opportunistic pathogens like Conclusion: We present a systematic, high-throughput profiling of oral microbiome with regard to long-term NG tube feeding among the older patient population.

Indexed as

16S rRNAamplicon sequence variantaspiration pneumonianasogastric tubeOral microbiome

Identifiers

PMID37063979
PMCPMC10101675
OpenAlexW4364380741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.