Evidence map›Paper›PMID 37063912›Full record

ArticleFrontiers in immunology2023

Autosomal recessive

Omaima Abdelmajeed, Muna Mohammed Dawoud Ali, Nahla Hashim Erwa, Alamin Mustafa, Yassin Abdelraheem Ahmed, Rogaia Hasap Alrasoul Ahmed, Hala Hamza Eltayeb Mohammed, Malaz Elsadeg Hassan, Monzir Ahmed, Shima Algam

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Class II Transactivator Gene (The application of clinical genetics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Omaima AbdelmajeedDepartment of Pediatrics, Omdurman Islamic University, Omdurman, Sudan.
Muna Mohammed Dawoud AliDepartment of Pediatrics, Tropical and Infectious Diseases, College of Medicine, University of Science and Technology, Khartoum, Sudan.
Nahla Hashim ErwaFaculty of Medicine, University of Khartoum, Khartoum, Sudan.
Alamin MustafaFaculty of Medicine, Al-Neelain University, Khartoum, Sudan.
Yassin Abdelraheem AhmedFaculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
Rogaia Hasap Alrasoul AhmedFaculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
Hala Hamza Eltayeb MohammedFaculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
Malaz Elsadeg HassanFaculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
Monzir AhmedFaculty of Medicine, Omdurman Islamic University, Omdurman, Sudan.
Shima AlgamFaculty of Medicine, Al-Neelain University, Khartoum, Sudan.
Omdurman Islamic University · SDAl-Neelain University · SDSudan University of Science and Technology · SDUniversity of Khartoum · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mendelian susceptibility to mycobacterial disease (MSMD) is a rare inherited condition characterized by selective susceptibility to weakly virulent mycobacteria, such as substrains of the bacille Calmette-Guérin (BCG) vaccine and different environmental mycobacteria. Case presentation: A 7-year-old Sudanese boy was referred to the immunology clinic with a suspected diagnosis of MSMD. This followed multiple presentations with disseminated tuberculosis and typhoid fever. Genetic testing surprisingly revealed pathogenic homozygous variants in Conclusion: It is challenging to diagnose MSMD, especially in developing countries where health systems are poor and have limited resources. Family history and genetic tests may help in early MSMD treatment and avoiding disease complications.

Indexed as

Genetic Predisposition to DiseaseMycobacterium InfectionsBCG VaccineChildFathersHumansMaleMutationReceptors, Interleukin-12BCG VaccineIL12RB1 protein, humanReceptors, Interleukin-12bacille Calmette–Guérin (BCG) vaccineIL12RB1 mutationimmunologyMendelian susceptibility to mycobacterial diseasestuberculosis

Identifiers

PMID37063912
PMCPMC10102344
OpenAlexW4362519232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.