Evidence map›Paper›PMID 37063855›Full record

ArticleFrontiers in immunology2023

Alterations in the gut virome in patients with ankylosing spondylitis.

Chen Li, Yan Zhang, Qiulong Yan, Ruochun Guo, Changming Chen, Shenghui Li, Yue Zhang, Jinxin Meng, Jie Ma, Wei You and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
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  7. Review
  8. Article
  9. Article
  10. Microbiology spectrum · 2025
    Article
  11. Review
  12. Characterization of the oral virome in patients with diabetes mellitus.Frontiers in cellular and infection microbiology · 2025
    Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Chen LiDepartment of Rheumatology, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yan ZhangDepartment of Traditional Chinese Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Qiulong YanDepartment of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Ruochun GuoPuensum Genetech Institute, Wuhan, China.
Changming ChenDepartment of Rheumatology and Immunology, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Shenghui LiPuensum Genetech Institute, Wuhan, China.
Yue ZhangDepartment of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Jinxin MengPuensum Genetech Institute, Wuhan, China.
Jie MaSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Wei YouBeijing Key Laboratory of Acupuncture Neuromodulation, Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Zhisong WuDepartment of Intensive Care Medicine, Dongfang Hospital Beijing University of Chinese Medicine, Beijing, China.
Wen SunSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNCapital Medical University · CNAffiliated Hospital of Guizhou Medical University · CNBeijing Hospital of Traditional Chinese Medicine · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Ankylosing spondylitis (AS), a chronic autoimmune disease, has been linked to the gut bacteriome. Methods: To investigate the characteristics of the gut virome in AS, we profiled the gut viral community of 193 AS patients and 59 healthy subjects based on a metagenome-wide analysis of fecal metagenomes from two publicly available datasets. Results: AS patients revealed a significant decrease in gut viral richness and a considerable alteration of the overall viral structure. At the family level, AS patients had an increased abundance of Discussion: This work provides novel insight into the AS gut virome, and the findings may guide future mechanistic and therapeutic studies for other autoimmune diseases.

Indexed as

Autoimmune DiseasesBacteriophagesGastrointestinal MicrobiomeSpondylitis, AnkylosingVirusesHumansViromeankylosing spondylitisgut viromemetagenome sequencingviral dysbiosisviral functionviral operational taxonomic units

Identifiers

PMID37063855
PMCPMC10098016
OpenAlexW4361276819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.