Evidence map›Paper›PMID 37063808›Full record

ArticleChemical science2023

Discovery of a photoactivatable dimerized STING agonist based on the benzo[

Dongyu Liu, Bin Yu, Xin Guan, Bin Song, Huikai Pan, Renbing Wang, Xi Feng, Lixia Pan, Huidan Huang, Zhe Wang and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Dongyu LiuDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Bin YuDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Xin GuanState Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences Nanning 530007 P. R. China.
Bin SongDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Huikai PanDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Renbing WangDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Xi FengDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Lixia PanState Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences Nanning 530007 P. R. China.
Huidan HuangDepartment of Pharmaceutical Engineering, School of Pharmacy, Wannan Medical College Wuhu China.
Zhe WangDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.ORCID https://orcid.org/0000-0002-7854-8207
Hongxi WuDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Zhixia QiuDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Zhiyu LiDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.
Jinlei BianDepartment of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University Nanjing 211100 P. R. China bianjl@cpu.edu.cn.ORCID https://orcid.org/0000-0003-4552-1195
China Pharmaceutical University · CNGuangxi Academy of Sciences · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimulator of interferon genes (STING) agonism presents a powerful weapon for cancer immunotherapy. This study reports a novel dimerized STING agonist diBSP01, which exhibited promising STING binding and activation properties

Identifiers

PMID37063808
PMCPMC10094158
OpenAlexW4324122282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.