Evidence map›Paper›PMID 37063480›Full record

ArticleMolecular therapy. Methods & clinical development2023

iPSC-derived neural precursor cells engineering

Yanyan Peng, Benjamin Liou, Yi Lin, Christopher N Mayhew, Sheila M Fleming, Ying Sun

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gaucher disease, state of the art and perspectives.Journal of internal medicine · 2025
    Review
  5. Dopamine Depletion in Parkinson's Disease and Therapeutic Options.CNS & neurological disorders drug targets · 2025
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yanyan PengDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Benjamin LiouDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Yi LinDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Christopher N MayhewDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Sheila M FlemingCollege of Pharmacy, Northeast Ohio Medical University, Rootstown, OH 44272, USA.
Ying SunDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Cincinnati Children's Hospital Medical Center · USNortheast Ohio Medical University · US

Funding

Progranulin: A Novel Gene in Gaucher DiseasesR01NS103931 · NINDS · YALE UNIVERSITY · PI Chuanju Liu, Ying Sun · 2017 to 2026
$4.3M
Gaucher disease:Treatment of neurodegenerative diseaseR01NS086134 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI PAN, DAO · 2013 to 2017
$2.1M
The Development of Small Molecule Inhibitors for Gaucher Disease Type 3UH2NS092981 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LARSEN, SCOTT D, SHAYMAN, JAMES ALAN · 2015 to 2015
$631k
Brain organoid modeling of Gaucher disease for identification of pathogenic pathways and therapy developmentR21HD102788 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI SUN, YING · 2020 to 2021
$437k
NICHD NIH HHS R21 HD102788NINDS NIH HHS R01 NS086134NINDS NIH HHS R01 NS103931NINDS NIH HHS UH2 NS092981
6 · The paper itself

Abstract

Mutations in

Indexed as

acid β-glucosidasealpha-synucleincell therapyneural precursor cellneurodegenerationneuronopathic Gaucher diseaseParkinson disease

Identifiers

PMID37063480
PMCPMC10102010
OpenAlexW4324342818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.