Evidence map›Paper›PMID 37063388›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Sensory impairment and algorithmic classification of early cognitive impairment.

Yurun Cai, Jennifer A Schrack, Alden L Gross, Nicole M Armstrong, Bonnielin K Swenor, Jennifer A Deal, Frank R Lin, Hang Wang, Qu Tian, Yang An and 4 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dual sensory impairment: Global prevalence, future projections, and its association with cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Article
  3. Review
  4. Relationship of Multiple Sensory Impairments With Physical Performance in Older Adults in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yurun CaiDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA.
Jennifer A SchrackDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA.
Alden L GrossDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA.
Nicole M ArmstrongDepartment of Psychiatry and Human Behavior Warren Alpert Medical School of Brown University Providence Rhode Island USA.
Bonnielin K SwenorWilmer Eye Institute Johns Hopkins School of Medicine Baltimore Maryland USA.
Jennifer A DealDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA.
Frank R LinCochlear Center for Hearing and Public Health Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA.
Hang WangCenter on Aging and Health Johns Hopkins School of Medicine Baltimore Maryland USA.
Qu TianIntramural Research Program National Institute on Aging Baltimore Maryland USA.
Yang AnIntramural Research Program National Institute on Aging Baltimore Maryland USA.
Eleanor M SimonsickIntramural Research Program National Institute on Aging Baltimore Maryland USA.
Luigi FerrucciIntramural Research Program National Institute on Aging Baltimore Maryland USA.
Susan M ResnickIntramural Research Program National Institute on Aging Baltimore Maryland USA.
Yuri AgrawalDepartment of Otolaryngology - Head and Neck Surgery Johns Hopkins School of Medicine Baltimore Maryland USA.

Funding

Early Markers of Alzheimer DiseaseZIAAG000185 · NIA · NATIONAL INSTITUTE ON AGING · PI WALKER, KEENAN · 2009 to 2025
$20.4M
Contribution of sensorimotor function to risk and pathogenic mechanisms of Alzheimer's disease and related dementiasR01AG061786 · NIA · JOHNS HOPKINS UNIVERSITY · PI AGRAWAL, YURI, LIN, FRANK R · 2019 to 2023
$3.7M
Energy Reserves, Physical Activity, and Alzheimer's Disease in the Baltimore Longitudinal Study of AgingU01AG057545 · NIA · JOHNS HOPKINS UNIVERSITY · PI SCHRACK, JENNIFER ANN · 2017 to 2021
$3.0M
Role and Mechanism of Hearing Impairment in Cognitive Decline and DementiaK01AG054693 · NIA · JOHNS HOPKINS UNIVERSITY · PI DEAL, JENNIFER ANNE · 2017 to 2022
$773k
Intersection of Physiologic Frailty and Cognitive Performance in Older Adults: An Integrative Data AnalysisK01AG050699 · NIA · JOHNS HOPKINS UNIVERSITY · PI GROSS, ALDEN L. · 2016 to 2020
$648k
NIA NIH HHS K01 AG050699NIA NIH HHS K01 AG054693NIA NIH HHS R01 AG061786NIA NIH HHS U01 AG057545
6 · The paper itself

Abstract

introductionSensory impairment (SI) is linked to cognitive decline, but its association with early cognitive impairment (ECI) is unclear.

methodsSensory functions (vision, hearing, vestibular function, proprioception, and olfaction) were measured between 2012 and 2018 in 414 Baltimore Longitudinal Study of Aging (BLSA) participants (age 74 ± 9 years; 55% women). ECI was defined as 1 standard deviation below age-, sex-, race-, and education-specific mean performance in Card Rotations or California Verbal Learning Test immediate recall. Log binomial models (cross-sectional analysis) and Cox regression models (time-to-event analysis) were used to examine the association between SI and ECI.

resultsCross-sectionally, participants with ≥3 SI had twice the prevalence of ECI (prevalence ratio = 2.10, DISCUSSION: SI is associated with higher prevalence, but not incident ECI. Future studies with large sample sizes need to further elucidate the relationship between SI and ECI. Highlights: Sensory impairment is associated with high prevalence of early cognitive impairmentMultisensory impairment may pose a strong risk of early changes in cognitive functionIdentifying multisensory impairment may help early detection of dementia.

Indexed as

cognitive impairmentneuropsychological testssensory function

Identifiers

PMID37063388
PMCPMC10103182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.