Evidence map›Paper›PMID 37063288›Full record

ArticleFrontiers in pharmacology2023

Transplacental passage of hyperforin, hypericin, and valerenic acid.

Deborah Spiess, Vanessa Fabienne Abegg, Antoine Chauveau, Joshua Rath, Andrea Treyer, Michael Reinehr, Sabrina Kuoni, Mouhssin Oufir, Olivier Potterat, Matthias Hamburger and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Diverse Therapeutic Potentials of Hypericin: An In-Depth Review.Current topics in medicinal chemistry · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Deborah SpiessDepartment of Obstetrics, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Vanessa Fabienne AbeggDivision of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Antoine ChauveauDivision of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Joshua RathDepartment of Obstetrics, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Andrea TreyerDivision of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Michael ReinehrDepartment of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
Sabrina KuoniDepartment of Obstetrics, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Mouhssin OufirDivision of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Olivier PotteratDivision of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Matthias HamburgerDivision of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Ana Paula Simões-WüstDepartment of Obstetrics, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safe medications for mild mental diseases in pregnancy are needed. Phytomedicines from St. John's wort and valerian are valid candidates, but safety data in pregnancy are lacking. The transplacental transport of hyperforin and hypericin (from St. John's wort), and valerenic acid (from valerian) was evaluated using the

Indexed as

hyperforinhypericinHypericum perforatumplacental perfusionpregnancyU(H)PLC-MS/MSvalerenic acidValeriana officinalis

Identifiers

PMID37063288
PMCPMC10103840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.