Evidence map›Paper›PMID 37063265›Full record

ReviewFrontiers in pharmacology2023

Non-coding RNAs: The recently accentuated molecules in the regulation of cell autophagy for ovarian cancer pathogenesis and therapeutic response.

Bi Peng, Jing Li, Yuanliang Yan, Yuanhong Liu, Qiuju Liang, Wei Liu, Abhimanyu Thakur, Kui Zhang, Zhijie Xu, Jian Wang and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Bi PengDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jing LiDepartment of Pharmacy, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Yuanliang YanDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yuanhong LiuDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qiuju LiangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Wei LiuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Abhimanyu ThakurBen May Department for Cancer Research, Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, United States.
Kui ZhangState Key Laboratory of Silkworm Genome Biology, Medical Research Institute, Southwest University, Chongqing, China.
Zhijie XuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jian WangDepartment of Pharmacy, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Fan ZhangDepartment of Gynecology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Central South University · CNXiangya Hospital Central South University · CNPudong New Area People's Hospital · CNSouthwest University · CNUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is a self-recycling and conserved process, in which the senescent cytoplasmic components are degraded in cells and then recycled to maintain homeostatic balance. Emerging evidence has suggested the involvement of autophagy in oncogenesis and progression of various cancers, such as ovarian cancer (OC). Meanwhile, the non-coding RNAs (ncRNAs) frequently regulate the mRNA transcription and other functional signaling pathways in cell autophagy, displaying promising roles in human cancer pathogenesis and therapeutic response. This article mainly reviews the cutting-edge research advances about the interactions between ncRNAs and autophagy in OC. This review not only summarizes the underlying mechanisms of dynamic ncRNA-autophagy association in OC, but also discusses their prognostic implications and therapeutic biomarkers. The aim of this review was to provide a more in-depth knowledge framework exploring the ncRNA-autophagy crosstalk and highlight the promising treatment strategies for OC patients.

Indexed as

cancer pathogenesiscell autophagynon-coding RNAsovarian cancerprognosis

Identifiers

PMID37063265
PMCPMC10102359
OpenAlexW4362519262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.