Evidence map›Paper›PMID 37063134›Full record

ArticleJTCVS open2023

The convergent cavopulmonary connection: A novel and efficient configuration of Fontan to accommodate mechanical support.

Pranava Sinha, Jacqueline Contento, Byeol Kim, Kevin Wang, Qiyuan Wu, Vincent Cleveland, Paige Mass, Yue-Hin Loke, Axel Krieger, Laura Olivieri

Abstract read
In one paragraph

Article in JTCVS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Applications of Computational Fluid Dynamics in Congenital Heart Disease: A Review.Journal of cardiovascular development and disease · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pranava SinhaDepartment of Pediatric Cardiac Surgery, M Health Fairview, University of Minnesota, Minneapolis, Minn.
Jacqueline ContentoSheikh Zayed Institute of Pediatric Surgical Innovation, Children's National Hospital, Washington, DC.
Byeol KimDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Md.
Kevin WangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Md.
Qiyuan WuDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Md.
Vincent ClevelandSheikh Zayed Institute of Pediatric Surgical Innovation, Children's National Hospital, Washington, DC.
Paige MassSheikh Zayed Institute of Pediatric Surgical Innovation, Children's National Hospital, Washington, DC.
Yue-Hin LokeSheikh Zayed Institute of Pediatric Surgical Innovation, Children's National Hospital, Washington, DC.
Axel KriegerDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Md.
Laura OlivieriSheikh Zayed Institute of Pediatric Surgical Innovation, Children's National Hospital, Washington, DC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The current total cavopulmonary connection Fontan has competing inflows and outflows, creating hemodynamic inefficiencies that contribute to Fontan failure and complicate placement and efficiency of mechanical circulatory support. We propose a novel convergent cavopulmonary connection (CCPC) Fontan design to create a single, converged venous outflow to the pulmonary arteries, thus increasing efficiency and mechanical circulatory support access. We then evaluate the feasibility and hemodynamic performance of the CCPC in various patient sizes using computational fluid dynamic assessments of computer-aided designs. Methods: Cardiac magnetic resonance imaging data from 12 patients with single ventricle (10 total cavopulmonary connection, 2 Glenn) physiology (body surface area, 0.5-2.0 m Results: All CCPC designs met hemodynamic performance thresholds for indexed power loss and hepatic flow distribution. CCPC designs showed improvements in reducing % nonphysiologic wall shear stress and balancing HFD. Conclusions: CCPC is physiologically and surgically feasible in various patient sizes using validated computational fluid dynamic models. CCPC configuration has analogous indexed power loss, hepatic flow distribution, and % nonphysiologic wall shear stress compared with total cavopulmonary connection, and the single inflow and outflow may ease mechanical circulatory support therapies. Further studies are required for design optimization and mechanical circulatory support institution.

Indexed as

computational fluid dynamicsFontan redesignhepatic flow distributionindexed power lossmechanical circulatory supportwall shear stress

Identifiers

PMID37063134
PMCPMC10091280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.