Evidence map›Paper›PMID 37063122›Full record

ArticleJTCVS open2023

The angiogenic gene profile of pulmonary endarterectomy specimens: Initial study.

Nezih Onur Ermerak, Betul Yilmaz, Saime Batirel, Sehnaz Olgun Yildizeli, Derya Kocakaya, Bulent Mutlu, Serpil Tas, Bedrettin Yildizeli

Abstract read
In one paragraph

Article in JTCVS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nezih Onur ErmerakDepartment of Thoracic Surgery, Marmara University School of Medicine, Istanbul, Turkey.
Betul YilmazDepartment of Biochemistry, Marmara University School of Medicine, Istanbul, Turkey.
Saime BatirelDepartment of Biochemistry, Marmara University School of Medicine, Istanbul, Turkey.
Sehnaz Olgun YildizeliDepartment of Biochemistry, Marmara University School of Medicine/Genetic and Metabolic Diseases Research and Investigation Center (GEMHAM), Marmara University, Istanbul, Turkey.
Derya KocakayaDepartment of Biochemistry, Marmara University School of Medicine/Genetic and Metabolic Diseases Research and Investigation Center (GEMHAM), Marmara University, Istanbul, Turkey.
Bulent MutluDepartment of Cardiology, Marmara University School of Medicine, Istanbul, Turkey.
Serpil TasDepartment of Cardiovascular Surgery, Kosuyolu Training and Research Hospital, Istanbul, Turkey.
Bedrettin YildizeliDepartment of Thoracic Surgery, Marmara University School of Medicine, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The underlying mechanisms for the development of chronic thromboembolic pulmonary hypertension and prognostic biomarkers are not clear yet. Thus, our aim is to assess and identify new biomarkers for the expression of 84 key genes linked to angiogenesis. Methods: Patients who had levels more than 1000 dynes·sec·cm Results: Eight patients (6 male, 2 female, median age 54.4 ± 13.1 years) who underwent pulmonary endarterectomy were included. Pulmonary vascular resistance improved significantly from 811 ± 390 dyn/s/cm Conclusions: These results can lead to the development of new markers that could predict adverse outcomes of patients with CTEPH. Identification of new markers that are related to worse outcomes would enable screening patients for early diagnosis and treatment.

Indexed as

angiogenesischronic thromboembolic pulmonary hypertensiongene expression

Identifiers

PMID37063122
PMCPMC10091285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.