Evidence map›Paper›PMID 37063035›Full record

ArticlePostgraduate medical journal2022

Effect of cigarette smoking on smoking biomarkers, blood pressure and blood lipid levels among Sri Lankan male smokers.

Prasanna Herath, Savithri Wimalasekera, Thamara Amarasekara, Manoj Fernando, Sue Turale

Open access · hybridAbstract read
In one paragraph

Article in Postgraduate medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Smoking status among hypertensive patients in Mosul City.Journal of education and health promotion · 2026
    Article
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  9. JSH2024 smoke-free declaration "Stop All Tobacco Products".Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Prasanna HerathDepartment of Nursing and Midwifery, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Ratmalana, Sri Lanka.ORCID 0000-0001-6470-2229
Savithri WimalasekeraDepartment of Physiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.ORCID 0000-0001-9179-4923
Thamara AmarasekaraDepartment of Nursing and Midwifery, Faculty of Allied Health Sciences University of Sri Jayewardenepura, Nugegoda, Sri Lanka.ORCID 0000-0003-0191-0973
Manoj FernandoDepartment of Health Promotion, Rajarata University of Sri Lanka, Mihintale, Anuradhapura, Sri Lanka.ORCID 0000-0002-0494-8769
Sue TuraleFaculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.ORCID 0000-0001-8704-5161
University of Sri Jayewardenepura · LKChiang Mai University · THGeneral Sir John Kotelawala Defence University · LKRajarata University of Sri Lanka · LK

Funding

University of Sri Jayewardenepura ASP/01/RE/MED/16/55
6 · The paper itself

Abstract

study purposeThe aim of this study was to determine the fractional exhaled nitric oxide (FeNO) levels, exhaled breath carbon monoxide (eCO) levels, blood pressure, blood lipid levels between smokers and non-smokers and to determine the association of smoking intensity with the above parameters.

methodsThis descriptive study was conducted in selected periurban areas of the Colombo District, Sri Lanka. Adult male current tobacco smokers (n=360), aged between 21 and 60 years were studied and compared with anthropometrically matched male non-smokers (n=180). Data were collected by interviewer-administered questionnaire, clinical assessment and measurement of FeNO by FENO monitor and eCO by Smokerlyser.

resultsSmokers had significantly lower mean FeNO levels and higher mean eCO values compared with non-smokers. Presentation of palpitations was higher among the smokers and a significantly positive correlation was identified between palpitations and eCO levels. There was a significantly positive correlation between the systolic blood pressure of smokers with the duration of smoking (DS), Brinkman Index (BI), Body Mass Index (BMI) and there was a significantly negative correlation with FeNO levels. The mean arterial pressure was positively correlated with the DS, BI and BMI. There was a significantly negative correlation between FeNO and the number of cigarettes smoked per day, DS and BI of smokers. Significantly higher total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), very LDL-C, TC: HDL ratio and low high density lipoprotein cholesterol (HDL-C) level was observed among smokers compared with the non-smokers.

conclusionsTobacco smoking was found to impact blood pressure and serum lipid levels thus enhancing the cardiovascular risk among smokers. The levels of eCO and FeNO are useful biomarkers for determining the intensity of smoking. The results indicate the necessity for urgent measures to stop cigarette smoking in Sri Lanka.

Indexed as

Cigarette SmokingAdultBiomarkersBlood PressureCholesterol, LDLHumansLipidsMaleMiddle AgedSmokersSri LankaYoung AdultBiomarkersCholesterol, LDLLipidscardiologyhypertension

Identifiers

PMID37063035
PMCPMC9613865
OpenAlexW3205843234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.