Evidence map›Paper›PMID 37062821›Full record

ArticleJournal of medical case reports2023

Successful management of poisoning with ivermectin (Mectizan) in the Obala health district (Centre Region, Cameroon): a case report.

Cyrille Donfo-Azafack, Hugues C Nana-Djeunga, Guy Wafeu-Sadeu, Raïssa Dongmo-Yemele, Joseph Kamgno

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Ivermectin and gynecologic cancer: What's the data?Gynecologic oncology reports · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cyrille Donfo-AzafackCentre for Research on Filariasis and other Tropical Diseases (CRFilMT), PO Box 5797, Yaoundé, Cameroon.
Hugues C Nana-DjeungaCentre for Research on Filariasis and other Tropical Diseases (CRFilMT), PO Box 5797, Yaoundé, Cameroon.ORCID http://orcid.org/0000-0002-4496-6048
Guy Wafeu-SadeuCentre for Research on Filariasis and other Tropical Diseases (CRFilMT), PO Box 5797, Yaoundé, Cameroon.
Raïssa Dongmo-YemeleCentre for Research on Filariasis and other Tropical Diseases (CRFilMT), PO Box 5797, Yaoundé, Cameroon.
Joseph KamgnoCentre for Research on Filariasis and other Tropical Diseases (CRFilMT), PO Box 5797, Yaoundé, Cameroon. kamgno@crfilmt.org.
International Institute of Tropical Agriculture · CMUniversité de Yaoundé I · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIvermectin (Mectizan) is an anthelmintic drug that plays a major role in the fight against two major filarial diseases, onchocerciasis and lymphatic filariasis. Unlike previous drugs that had serious and sometimes fatal side effects, ivermectin has been considered to be safe and, therefore, is widely used. Data reporting the clinical presentation of poisoning with ivermectin are very scanty, even in experimental studies. CASE PRESENTATION: In this paper, we report the case of a 19-year-old Black African female student residing in Obala (Centre Region, Cameroon) who was admitted to a health facility in Central Cameroon for a neurological disorder after intoxication with about 400 tablets of ivermectin 3 mg (~100 times the standard doses). This neurological disorder was characterized by somnolence, kinetic ataxia, increase of tendon reflex, and central visual disturbance. Management of this intoxication consisted of symptomatic treatment and monitoring of hemodynamic parameters for 5 days, with a favorable course.

conclusionsThis is the first report of a poisoning with ivermectin at ~100 times the recommended dose. This case report confirms the safety and tolerability of ivermectin, even at exceptionally high dose.

Indexed as

AnthelminticsNervous System DiseasesOnchocerciasisAdultCameroonFemaleHumansIvermectinYoung AdultAnthelminticsIvermectinCameroonCase reportIvermectinMectizanObala district hospitalPoisoning

Identifiers

PMID37062821
PMCPMC10108531
OpenAlexW4366004129

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.