Evidence map›Paper›PMID 37062564›Full record

ArticleAnalytica chimica acta2023

Molecular test for COVID-19 diagnosis based on a colorimetric genomagnetic assay.

Tássia Regina de Oliveira, Taíse Helena Oliveira Leite, Wyllian Neves Miranda, Erika Regina Manuli, Fábio Leal, Ester Sabino, Henrique Pott-Junior, Matias Melendez, Ronaldo Censi Faria

Open access · greenAbstract read
In one paragraph

Article in Analytica chimica acta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. DNA Polymerase I Large Fragment fromInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Tássia Regina de OliveiraDepartment of Chemistry, Federal University of São Carlos, São Carlos, SP, 13565-905, Brazil.
Taíse Helena Oliveira LeiteDepartment of Chemistry, Federal University of São Carlos, São Carlos, SP, 13565-905, Brazil.
Wyllian Neves MirandaDepartment of Chemistry, Federal University of São Carlos, São Carlos, SP, 13565-905, Brazil.
Erika Regina ManuliMunicipal University of São Caetano do Sul, São Caetano do Sul, SP, 09521-160, Brazil.
Fábio LealMunicipal University of São Caetano do Sul, São Caetano do Sul, SP, 09521-160, Brazil.
Ester SabinoInstitute of Tropical Medicine, University of São Paulo, São Paulo, SP, 05403-000, Brazil.
Henrique Pott-JuniorDepartment of Medicine, Federal University of São Carlos, São Carlos, SP, 13565-905, Brazil.
Matias MelendezCloning Solutions Ltda, Barretos, SP, 14780-459, Brazil; Molecular Carcinogenesis Program, National Cancer Institute, Rio de Janeiro, RJ, 20231-050, Brazil.
Ronaldo Censi FariaDepartment of Chemistry, Federal University of São Carlos, São Carlos, SP, 13565-905, Brazil. Electronic address: rcfaria@ufscar.br.
Universidade Federal de São Carlos · BRUniversidade Municipal de São Caetano do Sul · BRInstituto Nacional de Câncer - INCA · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The world is in a long pandemic period caused by the SARS-CoV-2 virus and massive diagnostic tests to assist efforts to control the spread of the disease and also to avoid new coronavirus variants are still needed. Herein, we propose a simple and accurate saliva-based colorimetric test for the diagnosis of COVID-19. Magnetic beads (MBs) modified with a sequence of single-strand DNA (ssDNA) complementary to the N gene of the SARS-CoV-2 RNA were developed and used for magnetic capture and separation from a complex saliva sample. A second biotinylated ssDNA sequence was applied, and the colorimetric detection was carried out by adding streptavidin-horseradish peroxidase conjugate, H

Indexed as

COVID-19ColorimetryCOVID-19 TestingHumansNucleic Acid Amplification TechniquesRNA, ViralSARS-CoV-2Sensitivity and SpecificityRNA, ViralColorimetric testCOVID-19Genomagnetic assaySARS-CoV-2

Identifiers

PMID37062564
PMCPMC10066033
OpenAlexW4362591007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.