ArticleCancer medicine2023
The Milan system for reporting salivary gland cytopathology-A single-center study of 2156 cases.
Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Diagnostic Utility of the Milan System for Reporting Salivary Gland Cytopathology With Cytohistological Correlation.Cytopathology : official journal of the British Society for Clinical Cytology · 2026Article
- Performance Characteristics of Milan System for Reporting Salivary Gland Cytopathology: An Experience From Western Saudi Population.Diagnostic cytopathology · 2026Article
- Fine-needle aspiration cytology reduces the frequency of surgeries for malignant salivary gland tumors.Cancer cytopathology · 2026Article
- Cytological features of oncocytic pleomorphic adenoma of the salivary gland: Using the Milan classification system to report 3 patients.Molecular and clinical oncology · 2025Article
- Cytological features of a lymphoepithelial cyst of the salivary gland with application of the second edition of Milan System for Reporting Salivary Gland Cytopathology.Molecular and clinical oncology · 2024Article
- The Milan system for reporting salivary gland cytopathology-A single-center study of 2156 cases.Cancer medicine · 2023Article
- The Second Edition of the Milan System for Reporting Salivary Gland Cytopathology: System Application, Outcome, and Cytohistological Correlation.Journal of cytologyArticle
- Article
- Preoperative cytopathological investigatory aids in the diagnosis of salivary gland lesions.Journal of oral and maxillofacial pathology : JOMFPReview
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9 authors.
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Abstract
backgroundFine-needle aspiration cytology (FNAC) represents an important diagnostic tool for the workup of salivary gland (SG) lesions. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is a six-tiered system for standardizing diagnoses and improvement of communication between pathologists and clinicians, providing risk of malignancy (ROM) rates for every category. The aims of the present study were (i) to validate the use of MSRSGC in a large series of SG FNAC in a tertiary center in Switzerland, (ii) to determine ROM for each category and compare them with data from MSRSGC and similar studies, and (iii) to investigate whether there were relevant differences of non-diagnostic results between fine-needle aspirations (FNA) performed by cytopathologists compared to non-cytopathologists.
methodsThe files of the department of Pathology in the University Hospital Zurich (UHZ) were searched for SG FNAC between 2010 and 2019. The MSRSGC guidelines were applied retrospectively. Furthermore, ROM, risk of neoplasia (RON), sensitivity, and specificity were calculated based on the cases with histopathological follow-up.
resultsA total of 2156 SG FNAC including 753 cases with histopathological follow-up were evaluated. Generally, ROM was within the range of values provided by MSRSGC, with some minor deviations. Sensitivity was 94.6%, and specificity was 99.3%.
conclusionsOur study confirms the usefulness of MSRSGC. In addition, it provides a detailed insight into the wide spectrum of SG FNAC. Finally, we showed that the rate of non-diagnostic FNA was significantly lower in FNAs performed by cytopathologists compared to non-cytopathologists.
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