Evidence map›Paper›PMID 37061627›Full record

Trial reportJournal of cancer research and clinical oncology2023

A randomized-controlled trial assessing the effect of intraoperative acupuncture on anesthesia-related parameters during gynecological oncology surgery.

Eran Ben-Arye, Irena Hirsh, Yakir Segev, Michael Grach, Viraj Master, Arie Eden, Noah Samuels, Nili Stein, Orit Gressel, Ludmila Ostrovsky and 4 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Fine-tuning the needle: analysis of acupuncturist response to alarming events during gynecological oncology surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Eran Ben-AryeIntegrative Oncology Program, The Oncology Service, Lin, Zebulun, and Carmel Medical Centers, Clalit Health Services, 35 Rothschild St, Haifa, Israel. eranben@netvision.net.il.
Irena HirshDepartment of Anesthesiology, Critical Care and Pain Medicine, Carmel Medical Center, Haifa, Israel.
Yakir SegevRappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Michael GrachDepartment of Anesthesiology, Critical Care and Pain Medicine, Carmel Medical Center, Haifa, Israel.
Viraj MasterDepartment of Urology and Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Arie EdenDepartment of Anesthesiology, Critical Care and Pain Medicine, Carmel Medical Center, Haifa, Israel.
Noah SamuelsCenter for Integrative Complementary Medicine, Faculty of Medicine, Shaarei Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.
Nili SteinDepartment of Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel.
Orit GresselIntegrative Oncology Program, The Oncology Service, Lin, Zebulun, and Carmel Medical Centers, Clalit Health Services, 35 Rothschild St, Haifa, Israel.
Ludmila OstrovskyDepartment of Obstetrics and Gynecology, Carmel Medical Center, Haifa, Israel.
Galit GalilIntegrative Oncology Program, The Oncology Service, Lin, Zebulun, and Carmel Medical Centers, Clalit Health Services, 35 Rothschild St, Haifa, Israel.
Meirav SchmidtDepartment of Anesthesiology, Critical Care and Pain Medicine, Carmel Medical Center, Haifa, Israel.
Elad SchiffRappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Ofer LavieRappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Carmel Medical Center · ILBnai Zion Medical Center · ILClalit Health Services · ILEmory University · USHebrew University of Jerusalem · ILRappaport Family Institute for Research in the Medical Sciences · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT AND

objectivesThe present study examined the impact of intraoperative acupuncture on anesthesia-related parameters in patients undergoing gynecological oncology surgery.

methodsParticipants underwent preoperative integrative oncology (IO) touch/relaxation treatments, followed by intraoperative acupuncture (Group A); preoperative IO treatments without acupuncture (Group B); or standard care only (Group C). Mean arterial pressure (MAP), heart rate (HR), MAP variability (mean of MAP standard deviation), bispectral index (BIS), and calculated blood pressure Average Real Variability (ARV) were measured intraoperatively.

resultsA total of 91 patients participated: Group A, 41; Group B, 24; Group C, 26. Among patients undergoing open laparotomy, Group A showed lower and more stable MAP and HR compared to Group B, (MAP, p = 0.026; HR, p = 0.029) and Group C (MAP, p = 0.025). Mean BIS, from incision to suture closing, was lower in Group A (vs. controls, p = 0.024). In patients undergoing laparoscopic surgery, MAP was elevated within Group A (p = 0.026) throughout surgery, with MAP variability significantly higher in Group A (P = 0.023) and Group B (P = 0.013) 10 min post-incision (vs. pre-incision). All groups showed similar intraoperative and post-anesthesia use of analgesic medication.

conclusionIntraoperative acupuncture was shown to reduce and stabilize MAP and HR, and reduce BIS in gynecology oncology patients undergoing laparotomy, with no impact on perioperative analgesic medication use. In the laparoscopic setting, intraoperative acupuncture was associated with elevated MAP. Further research is needed to explore the hemodynamic and BIS-associated benefits and risks of intraoperative acupuncture, and the impact on the use of analgesic drugs in response to these changes.

Indexed as

Acupuncture AnalgesiaAcupuncture TherapyAnesthesiaNeoplasmsAnalgesicsFemaleHumansAnalgesicsAcupunctureGynecological oncologyIntegrative medicineIntegrative oncologyIntraoperativePain

Identifiers

PMID37061627
PMCPMC10105534
OpenAlexW4365814718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.